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Life quality improvement of patients with non-small cell lung cancer undergoing targeted therapy: A case study of continuous care
To investigate the improvement effect of targeted therapy on non-small cell carcinoma patients life quality after the continuous nursing intervention. 104 non-small cell lung cancer patients in our hospital from July 2017 to November 2019 were allocated evenly and randomly into the control group (C)...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627644/ https://www.ncbi.nlm.nih.gov/pubmed/37932985 http://dx.doi.org/10.1097/MD.0000000000035678 |
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author | Min, Yonghua Zhu, Youcai Ye, Min Zhu, Qinya Xu, Yumei Li, Xiaofeng |
author_facet | Min, Yonghua Zhu, Youcai Ye, Min Zhu, Qinya Xu, Yumei Li, Xiaofeng |
author_sort | Min, Yonghua |
collection | PubMed |
description | To investigate the improvement effect of targeted therapy on non-small cell carcinoma patients life quality after the continuous nursing intervention. 104 non-small cell lung cancer patients in our hospital from July 2017 to November 2019 were allocated evenly and randomly into the control group (C) and the study group (S). By using clinical baseline data, quality of life questionnaire core 30 for cancer patients, evaluation of patient compliance behavior, the MOS item short-form health survey (SF-36), self rating depression scale (SDS), self rating anxiety scale (SAS), Overall Survival (OS) progression-free survival and adverse reaction symptoms were evaluated for the life quality of patients. There was comparability between the 2 sets of basic data. There was no significant difference in quality of life questionnaire core 30, SF-36, SAS, or SDS scores before treatment. After 3 months, there was a significant difference in the scores of various scales before treatment. At the same time, there was significant statistical significance before and after treatment in Group S. Their compliance rates were 84.62% and 98.08%. Adverse reactions incidence in Group S was lower. Taking a 2-year follow-up period as an example, significant statistical differences existed in OS and progression-free survival rates between adenocarcinoma and squamous carcinoma. SDS and SAS had high consistency in scoring with QLQ-30 and SF-36 scales. Targeted treatment for non-small cell carcinoma patients significantly improves their life quality and reduces the incidence of adverse reactions after continuous nursing intervention. |
format | Online Article Text |
id | pubmed-10627644 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-106276442023-11-07 Life quality improvement of patients with non-small cell lung cancer undergoing targeted therapy: A case study of continuous care Min, Yonghua Zhu, Youcai Ye, Min Zhu, Qinya Xu, Yumei Li, Xiaofeng Medicine (Baltimore) 5700 To investigate the improvement effect of targeted therapy on non-small cell carcinoma patients life quality after the continuous nursing intervention. 104 non-small cell lung cancer patients in our hospital from July 2017 to November 2019 were allocated evenly and randomly into the control group (C) and the study group (S). By using clinical baseline data, quality of life questionnaire core 30 for cancer patients, evaluation of patient compliance behavior, the MOS item short-form health survey (SF-36), self rating depression scale (SDS), self rating anxiety scale (SAS), Overall Survival (OS) progression-free survival and adverse reaction symptoms were evaluated for the life quality of patients. There was comparability between the 2 sets of basic data. There was no significant difference in quality of life questionnaire core 30, SF-36, SAS, or SDS scores before treatment. After 3 months, there was a significant difference in the scores of various scales before treatment. At the same time, there was significant statistical significance before and after treatment in Group S. Their compliance rates were 84.62% and 98.08%. Adverse reactions incidence in Group S was lower. Taking a 2-year follow-up period as an example, significant statistical differences existed in OS and progression-free survival rates between adenocarcinoma and squamous carcinoma. SDS and SAS had high consistency in scoring with QLQ-30 and SF-36 scales. Targeted treatment for non-small cell carcinoma patients significantly improves their life quality and reduces the incidence of adverse reactions after continuous nursing intervention. Lippincott Williams & Wilkins 2023-11-03 /pmc/articles/PMC10627644/ /pubmed/37932985 http://dx.doi.org/10.1097/MD.0000000000035678 Text en Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC) (https://creativecommons.org/licenses/by-nc/4.0/) , where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. |
spellingShingle | 5700 Min, Yonghua Zhu, Youcai Ye, Min Zhu, Qinya Xu, Yumei Li, Xiaofeng Life quality improvement of patients with non-small cell lung cancer undergoing targeted therapy: A case study of continuous care |
title | Life quality improvement of patients with non-small cell lung cancer undergoing targeted therapy: A case study of continuous care |
title_full | Life quality improvement of patients with non-small cell lung cancer undergoing targeted therapy: A case study of continuous care |
title_fullStr | Life quality improvement of patients with non-small cell lung cancer undergoing targeted therapy: A case study of continuous care |
title_full_unstemmed | Life quality improvement of patients with non-small cell lung cancer undergoing targeted therapy: A case study of continuous care |
title_short | Life quality improvement of patients with non-small cell lung cancer undergoing targeted therapy: A case study of continuous care |
title_sort | life quality improvement of patients with non-small cell lung cancer undergoing targeted therapy: a case study of continuous care |
topic | 5700 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627644/ https://www.ncbi.nlm.nih.gov/pubmed/37932985 http://dx.doi.org/10.1097/MD.0000000000035678 |
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