Cargando…

Effect of Tea Polyphenols, α-Lipoic Acid and Their Joint Use on the Antioxidant and Lipid Metabolism Performance of Hybrid Grouper (♀Epinephelus fuscoguttatus × ♂E. lanceolatu) Fed with High-Lipid Diets

This study investigated tea polyphenols (TP), α-lipoic acid (ALA) and their joint use on the antioxidant and lipid metabolic performance of hybrid grouper (♀Epinephelus fuscoguttatus × ♂E. lanceolatu) took food with high-fat diets. Six high-lipid diets with isonitrogen (50% of dry matter) and isolip...

Descripción completa

Detalles Bibliográficos
Autores principales: Suo, Xiangxiang, Yan, Xiaobo, Tan, Beiping, Pan, Simiao, Li, Tao, Liu, Hao, Huang, Weibin, Zhang, Shuang, Yang, Yuanzhi, Dong, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627718/
https://www.ncbi.nlm.nih.gov/pubmed/37936718
http://dx.doi.org/10.1155/2023/1393994
_version_ 1785131583193219072
author Suo, Xiangxiang
Yan, Xiaobo
Tan, Beiping
Pan, Simiao
Li, Tao
Liu, Hao
Huang, Weibin
Zhang, Shuang
Yang, Yuanzhi
Dong, Xiaohui
author_facet Suo, Xiangxiang
Yan, Xiaobo
Tan, Beiping
Pan, Simiao
Li, Tao
Liu, Hao
Huang, Weibin
Zhang, Shuang
Yang, Yuanzhi
Dong, Xiaohui
author_sort Suo, Xiangxiang
collection PubMed
description This study investigated tea polyphenols (TP), α-lipoic acid (ALA) and their joint use on the antioxidant and lipid metabolic performance of hybrid grouper (♀Epinephelus fuscoguttatus × ♂E. lanceolatu) took food with high-fat diets. Six high-lipid diets with isonitrogen (50% of dry matter) and isolipid (17% of dry value) were designed, in which a total content of 1,000 mg/kg additives were added to each group except for the control group (FL). The additives addition ratios in each group were ALA (AL), TP (PL), ALA : TP = 1 : 1 (EL), ALA : TP = 1 : 2 (OL), ALA : TP = 2 : 1 (TL). Each diet was divided into three repeat groups with 30 tails (6.84 ± 0.01 g) in each group and fed for 8 weeks. The consequences were as follows: (1) the highest weight gain rate, specific growth rate, as well as the lowest feed conversion ratio and ingestion rate were discovered in the OL team, which were opposite to the TL group. (2) The body fat content and muscle fat content in the fish oil group were the lowest (P < 0.05), while those of the TL group were the highest. (3) Serum catalase, glutathione peroxidase, total antioxidant capacity, and superoxide dismutase activities were the highest, and the content of reactive oxygen species was the lowest in the OL group. (4) The OL group has the highest hepatic lipase activity and the lowest very low-density lipoprotein content of the liver. In contrast, the TL group had the highest fatty acid synthetase (FAS) activity (P < 0.05). (5) The oil-red aspects of liver tissue displayed lipid particles in other groups were reduced to different degrees compared with FL group, and the OL group showed the best lipid-lowering effect. (6) Compared with the FL group, the relative expressions of FAS, acetyl-CoA carboxylase (acc), and apolipoprotein b-100 (apoB100) genes in the liver were decreased. The relative expressions of lipoprotein lipase (lpl) and peroxisome proliferators-activated receptors-α (pparα) genes related to lipid catabolism were increased, among which the OL group had the most significant change (P < 0.05). (7) According to the 7-day challenge test of Vibrio alginolyticus, the OL group had the highest survival rate. To sum up, both ALA and TP have positive effects on relieving the lipid metabolism disorder of hybrid grouper. If they are jointly used, adding ALA : TP in a ratio of 1 : 2 (OL) may have the best effect, and an addition ratio of 2 : 1 (TL) may inhibit the hybrid grouper growth and increase the feeding cost.
format Online
Article
Text
id pubmed-10627718
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-106277182023-11-07 Effect of Tea Polyphenols, α-Lipoic Acid and Their Joint Use on the Antioxidant and Lipid Metabolism Performance of Hybrid Grouper (♀Epinephelus fuscoguttatus × ♂E. lanceolatu) Fed with High-Lipid Diets Suo, Xiangxiang Yan, Xiaobo Tan, Beiping Pan, Simiao Li, Tao Liu, Hao Huang, Weibin Zhang, Shuang Yang, Yuanzhi Dong, Xiaohui Aquac Nutr Research Article This study investigated tea polyphenols (TP), α-lipoic acid (ALA) and their joint use on the antioxidant and lipid metabolic performance of hybrid grouper (♀Epinephelus fuscoguttatus × ♂E. lanceolatu) took food with high-fat diets. Six high-lipid diets with isonitrogen (50% of dry matter) and isolipid (17% of dry value) were designed, in which a total content of 1,000 mg/kg additives were added to each group except for the control group (FL). The additives addition ratios in each group were ALA (AL), TP (PL), ALA : TP = 1 : 1 (EL), ALA : TP = 1 : 2 (OL), ALA : TP = 2 : 1 (TL). Each diet was divided into three repeat groups with 30 tails (6.84 ± 0.01 g) in each group and fed for 8 weeks. The consequences were as follows: (1) the highest weight gain rate, specific growth rate, as well as the lowest feed conversion ratio and ingestion rate were discovered in the OL team, which were opposite to the TL group. (2) The body fat content and muscle fat content in the fish oil group were the lowest (P < 0.05), while those of the TL group were the highest. (3) Serum catalase, glutathione peroxidase, total antioxidant capacity, and superoxide dismutase activities were the highest, and the content of reactive oxygen species was the lowest in the OL group. (4) The OL group has the highest hepatic lipase activity and the lowest very low-density lipoprotein content of the liver. In contrast, the TL group had the highest fatty acid synthetase (FAS) activity (P < 0.05). (5) The oil-red aspects of liver tissue displayed lipid particles in other groups were reduced to different degrees compared with FL group, and the OL group showed the best lipid-lowering effect. (6) Compared with the FL group, the relative expressions of FAS, acetyl-CoA carboxylase (acc), and apolipoprotein b-100 (apoB100) genes in the liver were decreased. The relative expressions of lipoprotein lipase (lpl) and peroxisome proliferators-activated receptors-α (pparα) genes related to lipid catabolism were increased, among which the OL group had the most significant change (P < 0.05). (7) According to the 7-day challenge test of Vibrio alginolyticus, the OL group had the highest survival rate. To sum up, both ALA and TP have positive effects on relieving the lipid metabolism disorder of hybrid grouper. If they are jointly used, adding ALA : TP in a ratio of 1 : 2 (OL) may have the best effect, and an addition ratio of 2 : 1 (TL) may inhibit the hybrid grouper growth and increase the feeding cost. Hindawi 2023-10-30 /pmc/articles/PMC10627718/ /pubmed/37936718 http://dx.doi.org/10.1155/2023/1393994 Text en Copyright © 2023 Xiangxiang Suo et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Suo, Xiangxiang
Yan, Xiaobo
Tan, Beiping
Pan, Simiao
Li, Tao
Liu, Hao
Huang, Weibin
Zhang, Shuang
Yang, Yuanzhi
Dong, Xiaohui
Effect of Tea Polyphenols, α-Lipoic Acid and Their Joint Use on the Antioxidant and Lipid Metabolism Performance of Hybrid Grouper (♀Epinephelus fuscoguttatus × ♂E. lanceolatu) Fed with High-Lipid Diets
title Effect of Tea Polyphenols, α-Lipoic Acid and Their Joint Use on the Antioxidant and Lipid Metabolism Performance of Hybrid Grouper (♀Epinephelus fuscoguttatus × ♂E. lanceolatu) Fed with High-Lipid Diets
title_full Effect of Tea Polyphenols, α-Lipoic Acid and Their Joint Use on the Antioxidant and Lipid Metabolism Performance of Hybrid Grouper (♀Epinephelus fuscoguttatus × ♂E. lanceolatu) Fed with High-Lipid Diets
title_fullStr Effect of Tea Polyphenols, α-Lipoic Acid and Their Joint Use on the Antioxidant and Lipid Metabolism Performance of Hybrid Grouper (♀Epinephelus fuscoguttatus × ♂E. lanceolatu) Fed with High-Lipid Diets
title_full_unstemmed Effect of Tea Polyphenols, α-Lipoic Acid and Their Joint Use on the Antioxidant and Lipid Metabolism Performance of Hybrid Grouper (♀Epinephelus fuscoguttatus × ♂E. lanceolatu) Fed with High-Lipid Diets
title_short Effect of Tea Polyphenols, α-Lipoic Acid and Their Joint Use on the Antioxidant and Lipid Metabolism Performance of Hybrid Grouper (♀Epinephelus fuscoguttatus × ♂E. lanceolatu) Fed with High-Lipid Diets
title_sort effect of tea polyphenols, α-lipoic acid and their joint use on the antioxidant and lipid metabolism performance of hybrid grouper (♀epinephelus fuscoguttatus × ♂e. lanceolatu) fed with high-lipid diets
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627718/
https://www.ncbi.nlm.nih.gov/pubmed/37936718
http://dx.doi.org/10.1155/2023/1393994
work_keys_str_mv AT suoxiangxiang effectofteapolyphenolsalipoicacidandtheirjointuseontheantioxidantandlipidmetabolismperformanceofhybridgrouperepinephelusfuscoguttatuselanceolatufedwithhighlipiddiets
AT yanxiaobo effectofteapolyphenolsalipoicacidandtheirjointuseontheantioxidantandlipidmetabolismperformanceofhybridgrouperepinephelusfuscoguttatuselanceolatufedwithhighlipiddiets
AT tanbeiping effectofteapolyphenolsalipoicacidandtheirjointuseontheantioxidantandlipidmetabolismperformanceofhybridgrouperepinephelusfuscoguttatuselanceolatufedwithhighlipiddiets
AT pansimiao effectofteapolyphenolsalipoicacidandtheirjointuseontheantioxidantandlipidmetabolismperformanceofhybridgrouperepinephelusfuscoguttatuselanceolatufedwithhighlipiddiets
AT litao effectofteapolyphenolsalipoicacidandtheirjointuseontheantioxidantandlipidmetabolismperformanceofhybridgrouperepinephelusfuscoguttatuselanceolatufedwithhighlipiddiets
AT liuhao effectofteapolyphenolsalipoicacidandtheirjointuseontheantioxidantandlipidmetabolismperformanceofhybridgrouperepinephelusfuscoguttatuselanceolatufedwithhighlipiddiets
AT huangweibin effectofteapolyphenolsalipoicacidandtheirjointuseontheantioxidantandlipidmetabolismperformanceofhybridgrouperepinephelusfuscoguttatuselanceolatufedwithhighlipiddiets
AT zhangshuang effectofteapolyphenolsalipoicacidandtheirjointuseontheantioxidantandlipidmetabolismperformanceofhybridgrouperepinephelusfuscoguttatuselanceolatufedwithhighlipiddiets
AT yangyuanzhi effectofteapolyphenolsalipoicacidandtheirjointuseontheantioxidantandlipidmetabolismperformanceofhybridgrouperepinephelusfuscoguttatuselanceolatufedwithhighlipiddiets
AT dongxiaohui effectofteapolyphenolsalipoicacidandtheirjointuseontheantioxidantandlipidmetabolismperformanceofhybridgrouperepinephelusfuscoguttatuselanceolatufedwithhighlipiddiets