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Integrated analysis of DNA methylome and transcriptome reveals SFRP1 and LIPG as potential drivers of ovarian cancer metastasis

OBJECTIVE: More than 75% of ovarian cancer patients are diagnosed at advanced stages and die of tumor cell metastasis. This study aimed to identify new epigenetic and transcriptomic alterations associated with ovarian cancer metastasis. METHODS: Two cell sublines with low- and high-metastasis potent...

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Detalles Bibliográficos
Autores principales: Yi, Jiani, Wu, Mengting, Zheng, Zhihong, Zhou, Qing, Li, Xufan, Lu, Yan, Liu, Pengyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asian Society of Gynecologic Oncology; Korean Society of Gynecologic Oncology; Japan Society of Gynecologic Oncology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627750/
https://www.ncbi.nlm.nih.gov/pubmed/37417299
http://dx.doi.org/10.3802/jgo.2023.34.e71