Cargando…
Coronavirus disease 2019 related parosmia: an exploratory survey of demographics and treatment strategies
OBJECTIVE: To investigate the clinical features, therapeutic efficacy and symptom time course of post-coronavirus disease 2019 parosmia. METHODS: A 22-item online questionnaire was distributed to AbScent research group and Facebook coronavirus disease 2019 anosmia group adult members to assess clini...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627779/ https://www.ncbi.nlm.nih.gov/pubmed/37194063 http://dx.doi.org/10.1017/S0022215123000713 |
_version_ | 1785131601406984192 |
---|---|
author | Sowerby, L J Almubarak, Z Biadsee, A Rocha, T Hopkins, C |
author_facet | Sowerby, L J Almubarak, Z Biadsee, A Rocha, T Hopkins, C |
author_sort | Sowerby, L J |
collection | PubMed |
description | OBJECTIVE: To investigate the clinical features, therapeutic efficacy and symptom time course of post-coronavirus disease 2019 parosmia. METHODS: A 22-item online questionnaire was distributed to AbScent research group and Facebook coronavirus disease 2019 anosmia group adult members to assess clinical features, interventions and their subjective efficacy for parosmia. RESULTS: A total of 209 participants (86 per cent females) reported: smell loss on average 3 days after coronavirus symptoms, recovery 4 weeks later, and first parosmia symptoms 12 weeks post infection. Respondents reported 10 per cent body weight loss, and listed onion and garlic as significant parosmia triggers. Regarding quality of life, depression was the most cited item (54 per cent). Smell training was trialled by 74 per cent of participants, followed by nasal corticosteroid spray (49 per cent). Stellate ganglion block, trialled by 16 per cent of respondents, had the highest reported improvement (45 per cent), with 21 per cent reporting a sustained benefit – the highest rate amongst registered treatment options. CONCLUSION: Post-coronavirus parosmia has a significant impact and remains challenging to treat. Stellate ganglion block appears to be successful relative to other reported treatments. Further research into the pathophysiology, efficacy and mechanism of stellate ganglion block effect is warranted. |
format | Online Article Text |
id | pubmed-10627779 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cambridge University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-106277792023-11-07 Coronavirus disease 2019 related parosmia: an exploratory survey of demographics and treatment strategies Sowerby, L J Almubarak, Z Biadsee, A Rocha, T Hopkins, C J Laryngol Otol Main Article OBJECTIVE: To investigate the clinical features, therapeutic efficacy and symptom time course of post-coronavirus disease 2019 parosmia. METHODS: A 22-item online questionnaire was distributed to AbScent research group and Facebook coronavirus disease 2019 anosmia group adult members to assess clinical features, interventions and their subjective efficacy for parosmia. RESULTS: A total of 209 participants (86 per cent females) reported: smell loss on average 3 days after coronavirus symptoms, recovery 4 weeks later, and first parosmia symptoms 12 weeks post infection. Respondents reported 10 per cent body weight loss, and listed onion and garlic as significant parosmia triggers. Regarding quality of life, depression was the most cited item (54 per cent). Smell training was trialled by 74 per cent of participants, followed by nasal corticosteroid spray (49 per cent). Stellate ganglion block, trialled by 16 per cent of respondents, had the highest reported improvement (45 per cent), with 21 per cent reporting a sustained benefit – the highest rate amongst registered treatment options. CONCLUSION: Post-coronavirus parosmia has a significant impact and remains challenging to treat. Stellate ganglion block appears to be successful relative to other reported treatments. Further research into the pathophysiology, efficacy and mechanism of stellate ganglion block effect is warranted. Cambridge University Press 2023-11 2023-05-17 /pmc/articles/PMC10627779/ /pubmed/37194063 http://dx.doi.org/10.1017/S0022215123000713 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited. |
spellingShingle | Main Article Sowerby, L J Almubarak, Z Biadsee, A Rocha, T Hopkins, C Coronavirus disease 2019 related parosmia: an exploratory survey of demographics and treatment strategies |
title | Coronavirus disease 2019 related parosmia: an exploratory survey of demographics and treatment strategies |
title_full | Coronavirus disease 2019 related parosmia: an exploratory survey of demographics and treatment strategies |
title_fullStr | Coronavirus disease 2019 related parosmia: an exploratory survey of demographics and treatment strategies |
title_full_unstemmed | Coronavirus disease 2019 related parosmia: an exploratory survey of demographics and treatment strategies |
title_short | Coronavirus disease 2019 related parosmia: an exploratory survey of demographics and treatment strategies |
title_sort | coronavirus disease 2019 related parosmia: an exploratory survey of demographics and treatment strategies |
topic | Main Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627779/ https://www.ncbi.nlm.nih.gov/pubmed/37194063 http://dx.doi.org/10.1017/S0022215123000713 |
work_keys_str_mv | AT sowerbylj coronavirusdisease2019relatedparosmiaanexploratorysurveyofdemographicsandtreatmentstrategies AT almubarakz coronavirusdisease2019relatedparosmiaanexploratorysurveyofdemographicsandtreatmentstrategies AT biadseea coronavirusdisease2019relatedparosmiaanexploratorysurveyofdemographicsandtreatmentstrategies AT rochat coronavirusdisease2019relatedparosmiaanexploratorysurveyofdemographicsandtreatmentstrategies AT hopkinsc coronavirusdisease2019relatedparosmiaanexploratorysurveyofdemographicsandtreatmentstrategies |