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Does age impact outcomes of retrograde intrarenal surgery in the elderly? Results from 366 patients from the FLEXible ureteroscopy outcomes registry (FLEXOR)
BACKGROUND: There has been a consistent increase in the last decades in prevalence of renal stones in elderly. AIMS: To evaluate outcomes of retrograde intrarenal surgery (RIRS) for renal stones in elderly and factors associated with postoperative complications and residual fragments (RFs). METHODS:...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627914/ https://www.ncbi.nlm.nih.gov/pubmed/37682489 http://dx.doi.org/10.1007/s40520-023-02545-1 |
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author | Giulioni, Carlo Brocca, Carlo Gauhar, Vineet Somani, Bhaskar Kumar Chew, Ben Hall Traxer, Olivier Emiliani, Esteban Innoue, Takaki Sarica, Kemal Gadzhiev, Nariman Tanidir, Yiloren Teoh, Jeremy Yuen‑Chun Galosi, Andrea Benedetto Castellani, Daniele |
author_facet | Giulioni, Carlo Brocca, Carlo Gauhar, Vineet Somani, Bhaskar Kumar Chew, Ben Hall Traxer, Olivier Emiliani, Esteban Innoue, Takaki Sarica, Kemal Gadzhiev, Nariman Tanidir, Yiloren Teoh, Jeremy Yuen‑Chun Galosi, Andrea Benedetto Castellani, Daniele |
author_sort | Giulioni, Carlo |
collection | PubMed |
description | BACKGROUND: There has been a consistent increase in the last decades in prevalence of renal stones in elderly. AIMS: To evaluate outcomes of retrograde intrarenal surgery (RIRS) for renal stones in elderly and factors associated with postoperative complications and residual fragments (RFs). METHODS: Data from 12 centers were retrospectively reviewed. Inclusion criteria: ≥ 75 years, renal stones only, normal renal anatomy. Patients were divided into three groups; Group 1: patients aged 75–79 years; Group 2: age 80–84 years; Group 3: age ≥ 85 years. Multivariable logistic regression analyses were performed to assess factors associated with perioperative complications, sepsis, and RFs. RESULTS: 366 patients were included. There were 189 patients in Group 1, 113 in Group 2, and 64 in Group 3. There was no difference between groups regarding stone features and total surgical time. Median length of stay was significantly longer in Group 3 (6.0 days, vs 2.0 days in Group 2 vs 2.5 days in Group 1, p = 0.043). There was no significant difference in postoperative complications and RFs between the groups. At multivariable logistic regression analysis, female gender (OR 2.82) and maximum stone diameter (OR 1.14) were associated with higher odds of sepsis, while surgical time (OR 1.12) and the use of a reusable ureteroscope (OR 6.51) with overall complications. Stone size (OR 1.23) was associated with higher odds of RFs. CONCLUSION: RIRS showed safety and efficacy for kidney stones in elderly patients. Surgical time should be kept as short as possible to avoid higher odds of postoperative complications, particularly in females. |
format | Online Article Text |
id | pubmed-10627914 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-106279142023-11-08 Does age impact outcomes of retrograde intrarenal surgery in the elderly? Results from 366 patients from the FLEXible ureteroscopy outcomes registry (FLEXOR) Giulioni, Carlo Brocca, Carlo Gauhar, Vineet Somani, Bhaskar Kumar Chew, Ben Hall Traxer, Olivier Emiliani, Esteban Innoue, Takaki Sarica, Kemal Gadzhiev, Nariman Tanidir, Yiloren Teoh, Jeremy Yuen‑Chun Galosi, Andrea Benedetto Castellani, Daniele Aging Clin Exp Res Original Article BACKGROUND: There has been a consistent increase in the last decades in prevalence of renal stones in elderly. AIMS: To evaluate outcomes of retrograde intrarenal surgery (RIRS) for renal stones in elderly and factors associated with postoperative complications and residual fragments (RFs). METHODS: Data from 12 centers were retrospectively reviewed. Inclusion criteria: ≥ 75 years, renal stones only, normal renal anatomy. Patients were divided into three groups; Group 1: patients aged 75–79 years; Group 2: age 80–84 years; Group 3: age ≥ 85 years. Multivariable logistic regression analyses were performed to assess factors associated with perioperative complications, sepsis, and RFs. RESULTS: 366 patients were included. There were 189 patients in Group 1, 113 in Group 2, and 64 in Group 3. There was no difference between groups regarding stone features and total surgical time. Median length of stay was significantly longer in Group 3 (6.0 days, vs 2.0 days in Group 2 vs 2.5 days in Group 1, p = 0.043). There was no significant difference in postoperative complications and RFs between the groups. At multivariable logistic regression analysis, female gender (OR 2.82) and maximum stone diameter (OR 1.14) were associated with higher odds of sepsis, while surgical time (OR 1.12) and the use of a reusable ureteroscope (OR 6.51) with overall complications. Stone size (OR 1.23) was associated with higher odds of RFs. CONCLUSION: RIRS showed safety and efficacy for kidney stones in elderly patients. Surgical time should be kept as short as possible to avoid higher odds of postoperative complications, particularly in females. Springer International Publishing 2023-09-08 2023 /pmc/articles/PMC10627914/ /pubmed/37682489 http://dx.doi.org/10.1007/s40520-023-02545-1 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Original Article Giulioni, Carlo Brocca, Carlo Gauhar, Vineet Somani, Bhaskar Kumar Chew, Ben Hall Traxer, Olivier Emiliani, Esteban Innoue, Takaki Sarica, Kemal Gadzhiev, Nariman Tanidir, Yiloren Teoh, Jeremy Yuen‑Chun Galosi, Andrea Benedetto Castellani, Daniele Does age impact outcomes of retrograde intrarenal surgery in the elderly? Results from 366 patients from the FLEXible ureteroscopy outcomes registry (FLEXOR) |
title | Does age impact outcomes of retrograde intrarenal surgery in the elderly? Results from 366 patients from the FLEXible ureteroscopy outcomes registry (FLEXOR) |
title_full | Does age impact outcomes of retrograde intrarenal surgery in the elderly? Results from 366 patients from the FLEXible ureteroscopy outcomes registry (FLEXOR) |
title_fullStr | Does age impact outcomes of retrograde intrarenal surgery in the elderly? Results from 366 patients from the FLEXible ureteroscopy outcomes registry (FLEXOR) |
title_full_unstemmed | Does age impact outcomes of retrograde intrarenal surgery in the elderly? Results from 366 patients from the FLEXible ureteroscopy outcomes registry (FLEXOR) |
title_short | Does age impact outcomes of retrograde intrarenal surgery in the elderly? Results from 366 patients from the FLEXible ureteroscopy outcomes registry (FLEXOR) |
title_sort | does age impact outcomes of retrograde intrarenal surgery in the elderly? results from 366 patients from the flexible ureteroscopy outcomes registry (flexor) |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627914/ https://www.ncbi.nlm.nih.gov/pubmed/37682489 http://dx.doi.org/10.1007/s40520-023-02545-1 |
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