Cargando…

Thick artery–artery anastomoses delay the onset of selective fetal growth restriction in monochorionic diamniotic twins: a 7-year single-center cohort study

OBJECTIVE: This study aimed to investigate differences in placental characteristics between early- and late-onset selective fetal growth restriction (sFGR) in monochorionic diamniotic twins. METHODS: A total of 253 patients with sFGR between April 2013 and April 2020 were retrospectively analyzed. P...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xueju, Li, Luyao, Yuan, Pengbo, Zhao, Yangyu, Wei, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627941/
https://www.ncbi.nlm.nih.gov/pubmed/37942416
http://dx.doi.org/10.3389/fmed.2023.1265875
_version_ 1785131639801643008
author Wang, Xueju
Li, Luyao
Yuan, Pengbo
Zhao, Yangyu
Wei, Yuan
author_facet Wang, Xueju
Li, Luyao
Yuan, Pengbo
Zhao, Yangyu
Wei, Yuan
author_sort Wang, Xueju
collection PubMed
description OBJECTIVE: This study aimed to investigate differences in placental characteristics between early- and late-onset selective fetal growth restriction (sFGR) in monochorionic diamniotic twins. METHODS: A total of 253 patients with sFGR between April 2013 and April 2020 were retrospectively analyzed. Placental characteristics of early- and late-onset sFGR were compared. RESULTS: The gestational age at diagnosis and delivery in the early-onset group was significantly less than that in the late-onset group [22.0 (16.9–23.9) and 28.4 (24.0, 36.3) weeks, P < 0.001; 33.1 ± 2.2 and 33.7 ± 2.5 weeks, P = 0.025]. The birth weight of normal growth and growth-restricted fetuses in the early-onset group was less than the late-onset group [1,990 ± 422 and 2,162 ± 525 g, P = 0.044; 1,320 ± 409 and 1,595 ± 519 g, P = 0.001]. The birthweight discordance ratio in the early-onset group was greater than the late-onset group (0.34 ± 0.12 and 0.29 ± 0.13, P = 0.001). The early-onset group had a significantly lower prevalence of sFGR type I than the late-onset group (37.5 and 62.0%, P = 0.018). The early-onset group had a significantly higher prevalence of sFGR type III than the late-onset group (30.4 and 12.7%, P = 0.048). The early-onset group had a lower prevalence of thick artery–artery anastomoses than the late-onset group (37.5 and 62.0%, P = 0.006). The placental territory discordance ratio in the early-onset group was higher than in the late-onset group [0.60 (0.01, 0.80) and 0.50 (0.01, 0.88), P = 0.018]. CONCLUSION: Unequal placental territory is the cause for most of the late-onset sFGR. Thick artery–artery anastomoses may delay the onset time of these cases of sFGR.
format Online
Article
Text
id pubmed-10627941
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-106279412023-11-08 Thick artery–artery anastomoses delay the onset of selective fetal growth restriction in monochorionic diamniotic twins: a 7-year single-center cohort study Wang, Xueju Li, Luyao Yuan, Pengbo Zhao, Yangyu Wei, Yuan Front Med (Lausanne) Medicine OBJECTIVE: This study aimed to investigate differences in placental characteristics between early- and late-onset selective fetal growth restriction (sFGR) in monochorionic diamniotic twins. METHODS: A total of 253 patients with sFGR between April 2013 and April 2020 were retrospectively analyzed. Placental characteristics of early- and late-onset sFGR were compared. RESULTS: The gestational age at diagnosis and delivery in the early-onset group was significantly less than that in the late-onset group [22.0 (16.9–23.9) and 28.4 (24.0, 36.3) weeks, P < 0.001; 33.1 ± 2.2 and 33.7 ± 2.5 weeks, P = 0.025]. The birth weight of normal growth and growth-restricted fetuses in the early-onset group was less than the late-onset group [1,990 ± 422 and 2,162 ± 525 g, P = 0.044; 1,320 ± 409 and 1,595 ± 519 g, P = 0.001]. The birthweight discordance ratio in the early-onset group was greater than the late-onset group (0.34 ± 0.12 and 0.29 ± 0.13, P = 0.001). The early-onset group had a significantly lower prevalence of sFGR type I than the late-onset group (37.5 and 62.0%, P = 0.018). The early-onset group had a significantly higher prevalence of sFGR type III than the late-onset group (30.4 and 12.7%, P = 0.048). The early-onset group had a lower prevalence of thick artery–artery anastomoses than the late-onset group (37.5 and 62.0%, P = 0.006). The placental territory discordance ratio in the early-onset group was higher than in the late-onset group [0.60 (0.01, 0.80) and 0.50 (0.01, 0.88), P = 0.018]. CONCLUSION: Unequal placental territory is the cause for most of the late-onset sFGR. Thick artery–artery anastomoses may delay the onset time of these cases of sFGR. Frontiers Media S.A. 2023-10-24 /pmc/articles/PMC10627941/ /pubmed/37942416 http://dx.doi.org/10.3389/fmed.2023.1265875 Text en Copyright © 2023 Wang, Li, Yuan, Zhao and Wei. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Wang, Xueju
Li, Luyao
Yuan, Pengbo
Zhao, Yangyu
Wei, Yuan
Thick artery–artery anastomoses delay the onset of selective fetal growth restriction in monochorionic diamniotic twins: a 7-year single-center cohort study
title Thick artery–artery anastomoses delay the onset of selective fetal growth restriction in monochorionic diamniotic twins: a 7-year single-center cohort study
title_full Thick artery–artery anastomoses delay the onset of selective fetal growth restriction in monochorionic diamniotic twins: a 7-year single-center cohort study
title_fullStr Thick artery–artery anastomoses delay the onset of selective fetal growth restriction in monochorionic diamniotic twins: a 7-year single-center cohort study
title_full_unstemmed Thick artery–artery anastomoses delay the onset of selective fetal growth restriction in monochorionic diamniotic twins: a 7-year single-center cohort study
title_short Thick artery–artery anastomoses delay the onset of selective fetal growth restriction in monochorionic diamniotic twins: a 7-year single-center cohort study
title_sort thick artery–artery anastomoses delay the onset of selective fetal growth restriction in monochorionic diamniotic twins: a 7-year single-center cohort study
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627941/
https://www.ncbi.nlm.nih.gov/pubmed/37942416
http://dx.doi.org/10.3389/fmed.2023.1265875
work_keys_str_mv AT wangxueju thickarteryarteryanastomosesdelaytheonsetofselectivefetalgrowthrestrictioninmonochorionicdiamniotictwinsa7yearsinglecentercohortstudy
AT liluyao thickarteryarteryanastomosesdelaytheonsetofselectivefetalgrowthrestrictioninmonochorionicdiamniotictwinsa7yearsinglecentercohortstudy
AT yuanpengbo thickarteryarteryanastomosesdelaytheonsetofselectivefetalgrowthrestrictioninmonochorionicdiamniotictwinsa7yearsinglecentercohortstudy
AT zhaoyangyu thickarteryarteryanastomosesdelaytheonsetofselectivefetalgrowthrestrictioninmonochorionicdiamniotictwinsa7yearsinglecentercohortstudy
AT weiyuan thickarteryarteryanastomosesdelaytheonsetofselectivefetalgrowthrestrictioninmonochorionicdiamniotictwinsa7yearsinglecentercohortstudy