Cargando…
Microglia activation in periplaque white matter in multiple sclerosis depends on age and lesion type, but does not correlate with oligodendroglial loss
Multiple sclerosis (MS) is the most frequent inflammatory and demyelinating disease of the CNS. The disease course in MS is highly variable and driven by a combination of relapse-driven disease activity and relapse-independent disease progression. The formation of new focal demyelinating lesions is...
Autores principales: | Kessler, Wiebke, Thomas, Christian, Kuhlmann, Tanja |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628007/ https://www.ncbi.nlm.nih.gov/pubmed/37897549 http://dx.doi.org/10.1007/s00401-023-02645-2 |
Ejemplares similares
-
Paramagnetic rim lesions lead to pronounced diffuse periplaque white matter damage in multiple sclerosis
por: Krajnc, Nik, et al.
Publicado: (2023) -
Extrinsic immune cell-derived, but not intrinsic oligodendroglial factors contribute to oligodendroglial differentiation block in multiple sclerosis
por: Starost, Laura, et al.
Publicado: (2020) -
Significance and In Vivo Detection of Iron-Laden Microglia in White Matter Multiple Sclerosis Lesions
por: Gillen, Kelly M., et al.
Publicado: (2018) -
Loss of USP18 in microglia induces white matter pathology
por: Schwabenland, Marius, et al.
Publicado: (2019) -
Melatonin Promotes Oligodendroglial Maturation of Injured White Matter in Neonatal Rats
por: Olivier, Paul, et al.
Publicado: (2009)