Voluntary alcohol intake alters the motivation to seek intravenous oxycodone and neuronal activation during the reinstatement of oxycodone and sucrose seeking

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Opioid-alcohol polysubstance use is prevalent and worsens treatment outcomes. Here we assessed whether co-consumption of oxycodone and alcohol influence the intake of one another, demand for oxycodone, and the neurocircuitry underlying cue-primed reinstatement of oxycodone-seeking. Male and female r...

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Detalles Bibliográficos
Autores principales: Wilkinson, Courtney S., Blount, Harrison L., Davis, Shane, Rojas, Giselle, Wu, Lizhen, Murphy, Niall P., Schwendt, Marek, Knackstedt, Lori A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628226/
https://www.ncbi.nlm.nih.gov/pubmed/37932476
http://dx.doi.org/10.1038/s41598-023-46111-1
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