The DNA-binding induced (de)AMPylation activity of a Coxiella burnetii Fic enzyme targets Histone H3

The intracellular bacterial pathogen Coxiella burnetii evades the host response by secreting effector proteins that aid in establishing a replication-friendly niche. Bacterial filamentation induced by cyclic AMP (Fic) enzymes can act as effectors by covalently modifying target proteins with the post...

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Detalles Bibliográficos
Autores principales: Höpfner, Dorothea, Cichy, Adam, Pogenberg, Vivian, Krisp, Christoph, Mezouar, Soraya, Bach, Nina C., Grotheer, Jan, Zarza, Sandra Madariaga, Martinez, Eric, Bonazzi, Matteo, Feige, Matthias J., Sieber, Stephan A., Schlüter, Hartmut, Itzen, Aymelt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628234/
https://www.ncbi.nlm.nih.gov/pubmed/37932372
http://dx.doi.org/10.1038/s42003-023-05494-7

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