Cargando…

ChemR23 activation attenuates cognitive impairment in chronic cerebral hypoperfusion by inhibiting NLRP3 inflammasome-induced neuronal pyroptosis

Neuroinflammation plays critical roles in vascular dementia (VaD), the second leading cause of dementia, which can be induced by chronic cerebral hypoperfusion (CCH). NLRP3 inflammasome-induced pyroptosis, the inflammatory programmed cell death, has been reported to contribute to the development of...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yaxuan, Zhang, Jiawei, Zhao, Yao, Zhang, Yueqi, Liu, Lan, Xu, Xiaofeng, Wang, Xiuzhe, Fu, Jianliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628255/
https://www.ncbi.nlm.nih.gov/pubmed/37932279
http://dx.doi.org/10.1038/s41419-023-06237-6