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Combined in vitro/in vivo genome-wide CRISPR screens in triple negative breast cancer identify cancer stemness regulators in paclitaxel resistance

Triple negative breast cancer (TNBC) is defined as lacking the expressions of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). TNBC patients exhibit relatively poor clinical outcomes due to lack of molecular markers for targeted therapies. As s...

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Detalles Bibliográficos
Autores principales:	Yan, Gang, Dai, Meiou, Poulet, Sophie, Wang, Ni, Boudreault, Julien, Daliah, Girija, Ali, Suhad, Lebrun, Jean-Jacques
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628277/ https://www.ncbi.nlm.nih.gov/pubmed/37932309 http://dx.doi.org/10.1038/s41389-023-00497-9

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