Preneoplastic liver colonization by 11p15.5 altered mosaic cells in young children with hepatoblastoma

Pediatric liver tumors are very rare tumors with the most common diagnosis being hepatoblastoma. While hepatoblastomas are predominantly sporadic, around 15% of cases develop as part of predisposition syndromes such as Beckwith-Wiedemann (11p15.5 locus altered). Here, we identify mosaic genetic alte...

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Detalles Bibliográficos
Autores principales: Pilet, Jill, Hirsch, Theo Z., Gupta, Barkha, Roehrig, Amélie, Morcrette, Guillaume, Pire, Aurore, Letouzé, Eric, Fresneau, Brice, Taque, Sophie, Brugières, Laurence, Branchereau, Sophie, Chardot, Christophe, Aerts, Isabelle, Sarnacki, Sabine, Fabre, Monique, Guettier, Catherine, Rebouissou, Sandra, Zucman-Rossi, Jessica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628292/
https://www.ncbi.nlm.nih.gov/pubmed/37932266
http://dx.doi.org/10.1038/s41467-023-42418-9

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