Central pontine myelinolysis: a rare finding in hyperosmolar hyperglycemia

Central pontine myelinolysis (CPM) is a heterogeneous nervous system disease of pontine demyelination, usually caused by rapid correction of hyponatremia. In the present study, we report a unique case of a 46-year-old man with a hyperglycemic state complicated with CPM. MRI demonstrated a high signa...

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Autores principales: Qu, Hui-Ling, Sun, Xiao-Yu, Dai, Ying-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628315/
https://www.ncbi.nlm.nih.gov/pubmed/37941579
http://dx.doi.org/10.3389/fneur.2023.1216328
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author Qu, Hui-Ling
Sun, Xiao-Yu
Dai, Ying-Jie
author_facet Qu, Hui-Ling
Sun, Xiao-Yu
Dai, Ying-Jie
author_sort Qu, Hui-Ling
collection PubMed
description Central pontine myelinolysis (CPM) is a heterogeneous nervous system disease of pontine demyelination, usually caused by rapid correction of hyponatremia. In the present study, we report a unique case of a 46-year-old man with a hyperglycemic state complicated with CPM. MRI demonstrated a high signal on T2 and symmetric restricted diffusion in the pontine. In conclusion, the clinical case described confirmed that the hyperosmolar state inherent in hyperglycemia was a likely cause of CPM.
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spelling pubmed-106283152023-11-08 Central pontine myelinolysis: a rare finding in hyperosmolar hyperglycemia Qu, Hui-Ling Sun, Xiao-Yu Dai, Ying-Jie Front Neurol Neurology Central pontine myelinolysis (CPM) is a heterogeneous nervous system disease of pontine demyelination, usually caused by rapid correction of hyponatremia. In the present study, we report a unique case of a 46-year-old man with a hyperglycemic state complicated with CPM. MRI demonstrated a high signal on T2 and symmetric restricted diffusion in the pontine. In conclusion, the clinical case described confirmed that the hyperosmolar state inherent in hyperglycemia was a likely cause of CPM. Frontiers Media S.A. 2023-10-24 /pmc/articles/PMC10628315/ /pubmed/37941579 http://dx.doi.org/10.3389/fneur.2023.1216328 Text en Copyright © 2023 Qu, Sun and Dai. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Qu, Hui-Ling
Sun, Xiao-Yu
Dai, Ying-Jie
Central pontine myelinolysis: a rare finding in hyperosmolar hyperglycemia
title Central pontine myelinolysis: a rare finding in hyperosmolar hyperglycemia
title_full Central pontine myelinolysis: a rare finding in hyperosmolar hyperglycemia
title_fullStr Central pontine myelinolysis: a rare finding in hyperosmolar hyperglycemia
title_full_unstemmed Central pontine myelinolysis: a rare finding in hyperosmolar hyperglycemia
title_short Central pontine myelinolysis: a rare finding in hyperosmolar hyperglycemia
title_sort central pontine myelinolysis: a rare finding in hyperosmolar hyperglycemia
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628315/
https://www.ncbi.nlm.nih.gov/pubmed/37941579
http://dx.doi.org/10.3389/fneur.2023.1216328
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