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Conservative treatment of type A aortic dissection: a case report with 5 years of follow-up
BACKGROUND: Acute aortic dissection causes major morbidities and mortalities. The treatment of choice for type A aortic dissection (TAAD) is emergent surgical intervention. However, surgery per se may be associated with significant risk, in part due to the general surgical challenges, and the inhere...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628417/ https://www.ncbi.nlm.nih.gov/pubmed/37942037 http://dx.doi.org/10.21037/acr-22-107 |
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author | Arvin, Simon Ahmad, Khalil Tang, Mariann Andersen, Gratien Nørgaard, Bjarne Linde |
author_facet | Arvin, Simon Ahmad, Khalil Tang, Mariann Andersen, Gratien Nørgaard, Bjarne Linde |
author_sort | Arvin, Simon |
collection | PubMed |
description | BACKGROUND: Acute aortic dissection causes major morbidities and mortalities. The treatment of choice for type A aortic dissection (TAAD) is emergent surgical intervention. However, surgery per se may be associated with significant risk, in part due to the general surgical challenges, and the inherent hemodynamic- and organ malperfusion effects. In particular, surgery correlates with marked perioperative mortality in octo- and nonagenarians and those with severe comorbidities. Conservative medical treatment represents an alternative approach to patients for whom surgery is deemed high-risk, but case literature in this field remains sparse. CASE DESCRIPTION: We present a case of an 86-year-old female admitted with TAAD and deemed inoperable by the cardiothoracic surgical team due to excessive risks. The patient was treated conservatively with an extensive and aggressive antihypertensive regimen, leading to an uneventful recovery. CONCLUSIONS: Most cases of TAADs require emergent surgery. However, surgery is often contraindicated in comorbid and older patients due to excessive risks. The patient in this report is unique due to the long follow-up after conservative treatment and the close adherence to treatment protocol due to continuous therapeutic monitoring. It is important to consider factors for and against conservative therapeutic strategies, and, importantly, adherence to such should be carefully monitored to optimize patient outcomes. |
format | Online Article Text |
id | pubmed-10628417 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | AME Publishing Company |
record_format | MEDLINE/PubMed |
spelling | pubmed-106284172023-11-08 Conservative treatment of type A aortic dissection: a case report with 5 years of follow-up Arvin, Simon Ahmad, Khalil Tang, Mariann Andersen, Gratien Nørgaard, Bjarne Linde AME Case Rep Case Report BACKGROUND: Acute aortic dissection causes major morbidities and mortalities. The treatment of choice for type A aortic dissection (TAAD) is emergent surgical intervention. However, surgery per se may be associated with significant risk, in part due to the general surgical challenges, and the inherent hemodynamic- and organ malperfusion effects. In particular, surgery correlates with marked perioperative mortality in octo- and nonagenarians and those with severe comorbidities. Conservative medical treatment represents an alternative approach to patients for whom surgery is deemed high-risk, but case literature in this field remains sparse. CASE DESCRIPTION: We present a case of an 86-year-old female admitted with TAAD and deemed inoperable by the cardiothoracic surgical team due to excessive risks. The patient was treated conservatively with an extensive and aggressive antihypertensive regimen, leading to an uneventful recovery. CONCLUSIONS: Most cases of TAADs require emergent surgery. However, surgery is often contraindicated in comorbid and older patients due to excessive risks. The patient in this report is unique due to the long follow-up after conservative treatment and the close adherence to treatment protocol due to continuous therapeutic monitoring. It is important to consider factors for and against conservative therapeutic strategies, and, importantly, adherence to such should be carefully monitored to optimize patient outcomes. AME Publishing Company 2023-10-13 /pmc/articles/PMC10628417/ /pubmed/37942037 http://dx.doi.org/10.21037/acr-22-107 Text en 2023 AME Case Reports. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) . |
spellingShingle | Case Report Arvin, Simon Ahmad, Khalil Tang, Mariann Andersen, Gratien Nørgaard, Bjarne Linde Conservative treatment of type A aortic dissection: a case report with 5 years of follow-up |
title | Conservative treatment of type A aortic dissection: a case report with 5 years of follow-up |
title_full | Conservative treatment of type A aortic dissection: a case report with 5 years of follow-up |
title_fullStr | Conservative treatment of type A aortic dissection: a case report with 5 years of follow-up |
title_full_unstemmed | Conservative treatment of type A aortic dissection: a case report with 5 years of follow-up |
title_short | Conservative treatment of type A aortic dissection: a case report with 5 years of follow-up |
title_sort | conservative treatment of type a aortic dissection: a case report with 5 years of follow-up |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628417/ https://www.ncbi.nlm.nih.gov/pubmed/37942037 http://dx.doi.org/10.21037/acr-22-107 |
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