Cargando…

Conservative treatment of type A aortic dissection: a case report with 5 years of follow-up

BACKGROUND: Acute aortic dissection causes major morbidities and mortalities. The treatment of choice for type A aortic dissection (TAAD) is emergent surgical intervention. However, surgery per se may be associated with significant risk, in part due to the general surgical challenges, and the inhere...

Descripción completa

Detalles Bibliográficos
Autores principales: Arvin, Simon, Ahmad, Khalil, Tang, Mariann, Andersen, Gratien, Nørgaard, Bjarne Linde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628417/
https://www.ncbi.nlm.nih.gov/pubmed/37942037
http://dx.doi.org/10.21037/acr-22-107
_version_ 1785131753693773824
author Arvin, Simon
Ahmad, Khalil
Tang, Mariann
Andersen, Gratien
Nørgaard, Bjarne Linde
author_facet Arvin, Simon
Ahmad, Khalil
Tang, Mariann
Andersen, Gratien
Nørgaard, Bjarne Linde
author_sort Arvin, Simon
collection PubMed
description BACKGROUND: Acute aortic dissection causes major morbidities and mortalities. The treatment of choice for type A aortic dissection (TAAD) is emergent surgical intervention. However, surgery per se may be associated with significant risk, in part due to the general surgical challenges, and the inherent hemodynamic- and organ malperfusion effects. In particular, surgery correlates with marked perioperative mortality in octo- and nonagenarians and those with severe comorbidities. Conservative medical treatment represents an alternative approach to patients for whom surgery is deemed high-risk, but case literature in this field remains sparse. CASE DESCRIPTION: We present a case of an 86-year-old female admitted with TAAD and deemed inoperable by the cardiothoracic surgical team due to excessive risks. The patient was treated conservatively with an extensive and aggressive antihypertensive regimen, leading to an uneventful recovery. CONCLUSIONS: Most cases of TAADs require emergent surgery. However, surgery is often contraindicated in comorbid and older patients due to excessive risks. The patient in this report is unique due to the long follow-up after conservative treatment and the close adherence to treatment protocol due to continuous therapeutic monitoring. It is important to consider factors for and against conservative therapeutic strategies, and, importantly, adherence to such should be carefully monitored to optimize patient outcomes.
format Online
Article
Text
id pubmed-10628417
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher AME Publishing Company
record_format MEDLINE/PubMed
spelling pubmed-106284172023-11-08 Conservative treatment of type A aortic dissection: a case report with 5 years of follow-up Arvin, Simon Ahmad, Khalil Tang, Mariann Andersen, Gratien Nørgaard, Bjarne Linde AME Case Rep Case Report BACKGROUND: Acute aortic dissection causes major morbidities and mortalities. The treatment of choice for type A aortic dissection (TAAD) is emergent surgical intervention. However, surgery per se may be associated with significant risk, in part due to the general surgical challenges, and the inherent hemodynamic- and organ malperfusion effects. In particular, surgery correlates with marked perioperative mortality in octo- and nonagenarians and those with severe comorbidities. Conservative medical treatment represents an alternative approach to patients for whom surgery is deemed high-risk, but case literature in this field remains sparse. CASE DESCRIPTION: We present a case of an 86-year-old female admitted with TAAD and deemed inoperable by the cardiothoracic surgical team due to excessive risks. The patient was treated conservatively with an extensive and aggressive antihypertensive regimen, leading to an uneventful recovery. CONCLUSIONS: Most cases of TAADs require emergent surgery. However, surgery is often contraindicated in comorbid and older patients due to excessive risks. The patient in this report is unique due to the long follow-up after conservative treatment and the close adherence to treatment protocol due to continuous therapeutic monitoring. It is important to consider factors for and against conservative therapeutic strategies, and, importantly, adherence to such should be carefully monitored to optimize patient outcomes. AME Publishing Company 2023-10-13 /pmc/articles/PMC10628417/ /pubmed/37942037 http://dx.doi.org/10.21037/acr-22-107 Text en 2023 AME Case Reports. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Case Report
Arvin, Simon
Ahmad, Khalil
Tang, Mariann
Andersen, Gratien
Nørgaard, Bjarne Linde
Conservative treatment of type A aortic dissection: a case report with 5 years of follow-up
title Conservative treatment of type A aortic dissection: a case report with 5 years of follow-up
title_full Conservative treatment of type A aortic dissection: a case report with 5 years of follow-up
title_fullStr Conservative treatment of type A aortic dissection: a case report with 5 years of follow-up
title_full_unstemmed Conservative treatment of type A aortic dissection: a case report with 5 years of follow-up
title_short Conservative treatment of type A aortic dissection: a case report with 5 years of follow-up
title_sort conservative treatment of type a aortic dissection: a case report with 5 years of follow-up
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628417/
https://www.ncbi.nlm.nih.gov/pubmed/37942037
http://dx.doi.org/10.21037/acr-22-107
work_keys_str_mv AT arvinsimon conservativetreatmentoftypeaaorticdissectionacasereportwith5yearsoffollowup
AT ahmadkhalil conservativetreatmentoftypeaaorticdissectionacasereportwith5yearsoffollowup
AT tangmariann conservativetreatmentoftypeaaorticdissectionacasereportwith5yearsoffollowup
AT andersengratien conservativetreatmentoftypeaaorticdissectionacasereportwith5yearsoffollowup
AT nørgaardbjarnelinde conservativetreatmentoftypeaaorticdissectionacasereportwith5yearsoffollowup