Synaptic remodeling follows upper motor neuron hyperexcitability in a rodent model of TDP-43

Amyotrophic Lateral Sclerosis (ALS) is an incurable disease characterized by relentlessly progressive degeneration of the corticomotor system. Cortical hyperexcitability has been identified as an early pre-symptomatic biomarker of ALS. This suggests that hyperexcitability occurs upstream in the ALS...

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Detalles Bibliográficos
Autores principales: Dyer, Marcus S., Odierna, G. Lorenzo, Clark, Rosemary M., Woodhouse, Adele, Blizzard, Catherine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628445/
https://www.ncbi.nlm.nih.gov/pubmed/37941604
http://dx.doi.org/10.3389/fncel.2023.1274979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628445/
https://www.ncbi.nlm.nih.gov/pubmed/37941604
http://dx.doi.org/10.3389/fncel.2023.1274979

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