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Synaptic remodeling follows upper motor neuron hyperexcitability in a rodent model of TDP-43

Amyotrophic Lateral Sclerosis (ALS) is an incurable disease characterized by relentlessly progressive degeneration of the corticomotor system. Cortical hyperexcitability has been identified as an early pre-symptomatic biomarker of ALS. This suggests that hyperexcitability occurs upstream in the ALS...

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Detalles Bibliográficos
Autores principales:	Dyer, Marcus S., Odierna, G. Lorenzo, Clark, Rosemary M., Woodhouse, Adele, Blizzard, Catherine A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Cellular Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628445/ https://www.ncbi.nlm.nih.gov/pubmed/37941604 http://dx.doi.org/10.3389/fncel.2023.1274979

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