Cargando…

Dexamethasone impairs the expression of antimicrobial mediators in lipopolysaccharide-activated primary macrophages by inhibiting both expression and function of interferon β

Glucocorticoids potently inhibit expression of many inflammatory mediators, and have been widely used to treat both acute and chronic inflammatory diseases for more than seventy years. However, they can have several unwanted effects, amongst which immunosuppression is one of the most common. Here we...

Descripción completa

Detalles Bibliográficos
Autores principales:	O’Neil, John D., Bolimowska, Oliwia O., Clayton, Sally A., Tang, Tina, Daley, Kalbinder K., Lara-Reyna, Samuel, Warner, Jordan, Martin, Claire S., Mahida, Rahul Y., Hardy, Rowan S., Arthur, J. Simon C., Clark, Andrew R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628473/ https://www.ncbi.nlm.nih.gov/pubmed/37942320 http://dx.doi.org/10.3389/fimmu.2023.1190261

Ejemplares similares

Bacterial lipopolysaccharide (endotoxin) enhances expression and secretion of beta 2 interferon by human fibroblasts
Publicado: (1987)

Azithromycin suppresses interleukin-12p40 expression in lipopolysaccharide and interferon-γ stimulated macrophages
por: Yamauchi, Keiko, et al.
Publicado: (2009)

Methylprednisolone inhibits interleukin-17 and interferon-gamma expression by both naive and primed T cells
por: Momčilović, Miljana, et al.
Publicado: (2008)

Dexamethasone Pretreatment Alleviates Isoniazid/Lipopolysaccharide Hepatotoxicity: Inhibition of Inflammatory and Oxidative Stress
por: Hassan, Hozeifa M., et al.
Publicado: (2017)

Disposition and effect of intra-articularly administered dexamethasone on lipopolysaccharide induced equine synovitis
por: Ekstrand, Carl, et al.
Publicado: (2019)

Interferon Regulatory Factor 5 Mediates Lipopolysaccharide-Induced Neuroinflammation
por: Fan, Ziqi, et al.
Publicado: (2020)

Dexamethasone modulates immature neutrophils and interferon programming in severe COVID-19
por: Sinha, Sarthak, et al.
Publicado: (2021)

Dexamethasone attenuates interferon-related cytokine hyperresponsiveness in COVID-19 patients
por: Engel, Job J., et al.
Publicado: (2023)

Assessment of Alveolar Macrophage Dysfunction Using an in vitro Model of Acute Respiratory Distress Syndrome
por: Mahida, Rahul Y., et al.
Publicado: (2021)

Lipopolysaccharide and Tumor Necrosis Factor Alpha Inhibit Interferon Signaling in Hepatocytes by Increasing Ubiquitin-Like Protease 18 (USP18) Expression
por: MacParland, Sonya A., et al.
Publicado: (2016)

Vitamin D both facilitates and attenuates the cellular response to lipopolysaccharide
por: Chen, Ling, et al.
Publicado: (2017)

Interferon gamma and lipopolysaccharide promote macrophage adherence to basement membrane glycoproteins
Publicado: (1989)

Dexamethasone/gemcitabine/interferon-alpha: COVID-19 infection: 2 case reports
Publicado: (2021)

Effects of Postnatal Dexamethasone or Hydrocortisone in a Rat Model of Antenatal Lipopolysaccharide and Neonatal Hyperoxia Exposure
por: Lee, Hyun Ju, et al.
Publicado: (2012)

Effects of Dexamethasone and Cox Inhibitors on Intracranial Pressure and Cerebral Perfusion in the Lipopolysaccharide Treated Rats with Hyperammonemia
por: Rohde, Johan, et al.
Publicado: (2015)

Genes Involved by Dexamethasone in Prevention of Long-Term Memory Impairment Caused by Lipopolysaccharide-Induced Neuroinflammation
por: Shishkina, Galina T., et al.
Publicado: (2023)

Alnus Sibirica Extracts Suppress the Expression of Inflammatory Cytokines Induced by Lipopolysaccharides, Tumor Necrosis Factor-α, and Interferon-γ in Human Dermal Fibroblasts
por: Choi, Jeongyoon, et al.
Publicado: (2019)

Acute respiratory distress syndrome is associated with impaired alveolar macrophage efferocytosis
por: Mahida, Rahul Y., et al.
Publicado: (2021)

Inflammation causes remodeling of mitochondrial cytochrome c oxidase mediated by the bifunctional gene C15orf48
por: Clayton, Sally A., et al.
Publicado: (2021)

Gene Expression Profiling Identifies Interferon Signalling Molecules and IGFBP3 in Human Degenerative Annulus Fibrosus
por: Kazezian, Zepur, et al.
Publicado: (2015)

Interferon gamma inhibits both proliferation and expression of differentiation-specific alpha-smooth muscle actin in arterial smooth muscle cells
Publicado: (1989)

LPAIV H9N2 Drives the Differential Expression of Goose Interferons and Proinflammatory Cytokines in Both In Vitro and In Vivo Studies
por: Zhou, Hao, et al.
Publicado: (2016)

Effect of Glycine on BV-2 Microglial Cells Treated with Interferon-γ and Lipopolysaccharide
por: Egger, Florentina, et al.
Publicado: (2020)

Panaxadiol Saponin and Dexamethasone Improve Renal Function in Lipopolysaccharide-Induced Mouse Model of Acute Kidney Injury
por: Chen, Yan, et al.
Publicado: (2015)

Granulocyte colony-stimulating factor blockade enables dexamethasone to inhibit lipopolysaccharide-induced murine lung neutrophils
por: Banuelos, Jesus, et al.
Publicado: (2017)

Constitutive metanephric mesenchyme-specific expression of interferon-gamma causes renal dysplasia by regulating Sall1 expression
por: Yun, Kangsun, et al.
Publicado: (2018)

Stochastic Expression of the Interferon-β Gene
por: Zhao, Mingwei, et al.
Publicado: (2012)

Lipopolysaccharide induces expression of collagen VI in the rat lung
por: Okawa, Sayuri, et al.
Publicado: (2014)

Gene expression patterns in bone following lipopolysaccharide stimulation
por: Yang, Jing, et al.
Publicado: (2014)

Dexamethasone stimulates expression of C-type Natriuretic Peptide in chondrocytes
por: Agoston, Hanga, et al.
Publicado: (2006)

PTGDR gene expression and response to dexamethasone treatment in an in vitro model
por: Marcos-Vadillo, Elena, et al.
Publicado: (2017)

The Effect of Divergence in Feed Efficiency on the Intestinal Microbiota and the Intestinal Immune Response in Both Unchallenged and Lipopolysaccharide Challenged Ileal and Colonic Explants
por: Vigors, Stafford, et al.
Publicado: (2016)

Silencing Dkk1 expression rescues dexamethasone-induced suppression of primary human osteoblast differentiation
por: Butler, Joseph S, et al.
Publicado: (2010)

Both TLR2 and TRIF Contribute to Interferon-β Production during Listeria Infection
por: Aubry, Camille, et al.
Publicado: (2012)

Licocalchone-C Extracted from Glycyrrhiza Glabra Inhibits Lipopolysaccharide-Interferon-γ Inflammation by Improving Antioxidant Conditions and Regulating Inducible Nitric Oxide Synthase Expression
por: Franceschelli, Sara, et al.
Publicado: (2011)

Comparative Effects of Dexamethasone and Meloxicam on Magnitude of the Acute Inflammatory Response Induced by Escherichia coli Lipopolysaccharide in Broiler Chickens
por: Manzari Tavakoli, Mohadeseh, et al.
Publicado: (2020)

Macrophage activation by lipopolysaccharide, interferon-γ and interleukin-4: effect of fatty acid metabolism
por: Darmani, H., et al.
Publicado: (1995)

Lack of binding of bacterial lipopolysaccharide to mouse lung macrophages and restoration of binding by gamma interferon
Publicado: (1985)

Dexamethasone Attenuates the Expression of MMP-13 in Chondrocytes through MKP-1
por: Lehtola, Tiina, et al.
Publicado: (2022)

Dexamethasone enhances CD163 expression in porcine IPKM immortalized macrophages
por: Takenouchi, Takato, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_cnv3sr92jp6naqobl2hf9ai52a