Cell type dependent stability and virulence of a recombinant SARS-CoV-2, and engineering of a propagation deficient RNA replicon to analyze virus RNA synthesis

Engineering of reverse genetics systems for newly emerged viruses allows viral genome manipulation, being an essential tool for the study of virus life cycle, virus-host interactions and pathogenesis, as well as for the development of effective antiviral strategies. Severe acute respiratory syndrome...

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Detalles Bibliográficos
Autores principales: Wang, Li, Guzman, María, Muñoz-Santos, Diego, Honrubia, Jose Manuel, Ripoll-Gomez, Jorge, Delgado, Rafael, Sola, Isabel, Enjuanes, Luis, Zuñiga, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628495/
https://www.ncbi.nlm.nih.gov/pubmed/37942479
http://dx.doi.org/10.3389/fcimb.2023.1268227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628495/
https://www.ncbi.nlm.nih.gov/pubmed/37942479
http://dx.doi.org/10.3389/fcimb.2023.1268227

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