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Metabolomics analysis of human cumulus cells obtained from cumulus–oocyte complexes with different developmental potential

STUDY QUESTION: Is the abundance of certain biochemical compounds in human cumulus cells (CCs) related to oocyte quality? SUMMARY ANSWER: Malonate, 5-oxyproline, and erythronate were positively associated with pregnancy potential. WHAT IS KNOWN ALREADY: CCs are removed and discarded prior to ICSI, t...

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Detalles Bibliográficos
Autores principales: Martínez-Moro, Álvaro, González-Brusi, Leopoldo, Querejeta-Fernández, Ana, Padilla-Ruiz, Ester, García-Blanco, Javier, Bermejo-Álvarez, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628504/
https://www.ncbi.nlm.nih.gov/pubmed/37697661
http://dx.doi.org/10.1093/humrep/dead181