Bevacizumab, Irinotecan, and Biweekly Trifluridine/Tipiracil for Metastatic Colorectal Cancer: MODURATE, a Phase Ib Study

BACKGROUND: In this phase Ib study MODURATE, we optimized the dosing schedule and tested the efficacy and safety of trifluridine/tipiracil, irinotecan, and bevacizumab in patients with metastatic colorectal cancer with fluoropyrimidine and oxaliplatin treatment failure. METHODS: We included a dose e...

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Detalles Bibliográficos
Autores principales: Taniguchi, Hiroya, Yamazaki, Kentaro, Masuishi, Toshiki, Kawakami, Takeshi, Onozawa, Yusuke, Honda, Kazunori, Kadowaki, Shigenori, Narita, Yukiya, Tsushima, Takahiro, Hamauchi, Satoshi, Todaka, Akiko, Yokota, Tomoya, Ando, Masashi, Mori, Keita, Shirasu, Hiromichi, Yasui, Hirofumi, Muro, Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Clinical Trial Results
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628564/
https://www.ncbi.nlm.nih.gov/pubmed/37284901
http://dx.doi.org/10.1093/oncolo/oyad143

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