The roles of T cells in psoriasis

Psoriasis is a recurring inflammatory skin condition characterized by scaly, red patches on the skin. It affects approximately 3% of the US population and is associated with histological changes such as epidermal hyperplasia, increased blood vessel proliferation, and infiltration of leukocytes into...

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Autores principales: Zhang, Peng, Su, Yuwen, Li, Siying, Chen, Hui, Wu, Ruifang, Wu, Haijing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628572/
https://www.ncbi.nlm.nih.gov/pubmed/37942312
http://dx.doi.org/10.3389/fimmu.2023.1081256
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author Zhang, Peng
Su, Yuwen
Li, Siying
Chen, Hui
Wu, Ruifang
Wu, Haijing
author_facet Zhang, Peng
Su, Yuwen
Li, Siying
Chen, Hui
Wu, Ruifang
Wu, Haijing
author_sort Zhang, Peng
collection PubMed
description Psoriasis is a recurring inflammatory skin condition characterized by scaly, red patches on the skin. It affects approximately 3% of the US population and is associated with histological changes such as epidermal hyperplasia, increased blood vessel proliferation, and infiltration of leukocytes into the skin’s dermis. T cells, which are classified into various subtypes, have been found to play significant roles in immune-mediated diseases, particularly psoriasis. This paper provides a review of the different T lymphocyte subtypes and their functions in psoriasis, as well as an overview of targeted therapies for treating psoriasis.
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spelling pubmed-106285722023-11-08 The roles of T cells in psoriasis Zhang, Peng Su, Yuwen Li, Siying Chen, Hui Wu, Ruifang Wu, Haijing Front Immunol Immunology Psoriasis is a recurring inflammatory skin condition characterized by scaly, red patches on the skin. It affects approximately 3% of the US population and is associated with histological changes such as epidermal hyperplasia, increased blood vessel proliferation, and infiltration of leukocytes into the skin’s dermis. T cells, which are classified into various subtypes, have been found to play significant roles in immune-mediated diseases, particularly psoriasis. This paper provides a review of the different T lymphocyte subtypes and their functions in psoriasis, as well as an overview of targeted therapies for treating psoriasis. Frontiers Media S.A. 2023-10-24 /pmc/articles/PMC10628572/ /pubmed/37942312 http://dx.doi.org/10.3389/fimmu.2023.1081256 Text en Copyright © 2023 Zhang, Su, Li, Chen, Wu and Wu https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Zhang, Peng
Su, Yuwen
Li, Siying
Chen, Hui
Wu, Ruifang
Wu, Haijing
The roles of T cells in psoriasis
title The roles of T cells in psoriasis
title_full The roles of T cells in psoriasis
title_fullStr The roles of T cells in psoriasis
title_full_unstemmed The roles of T cells in psoriasis
title_short The roles of T cells in psoriasis
title_sort roles of t cells in psoriasis
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628572/
https://www.ncbi.nlm.nih.gov/pubmed/37942312
http://dx.doi.org/10.3389/fimmu.2023.1081256
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