Syndecan-1 shedding destroys epithelial adherens junctions through STAT3 after renal ischemia/reperfusion injury

Adherens junctions between tubular epithelial cells are disrupted in renal ischemia/reperfusion (I/R) injury. Syndecan-1 (SDC-1) is involved in maintaining cell morphology. We aimed to study the role of SDC-1 shedding induced by renal I/R in the destruction of intracellular adherens junctions. We fo...

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Detalles Bibliográficos
Autores principales: Guo, Man, Shen, Daoqi, Su, Yiqi, Xu, Jiarui, Zhao, Shuan, Zhang, Weidong, Wang, Yaqiong, Jiang, Wuhua, Wang, Jialin, Geng, Xuemei, Ding, Xiaoqiang, Xu, Xialian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628745/
https://www.ncbi.nlm.nih.gov/pubmed/37942007
http://dx.doi.org/10.1016/j.isci.2023.108211

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