APOE Genotype and Alzheimer Disease Risk Across Age, Sex, and Population Ancestry

IMPORTANCE: Apolipoprotein E (APOE)*2 and APOE*4 are, respectively, the strongest protective and risk-increasing, common genetic variants for late-onset Alzheimer disease (AD), making APOE status highly relevant toward clinical trial design and AD research broadly. The associations of APOE genotypes...

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Detalles Bibliográficos
Autores principales: Belloy, Michael E., Andrews, Shea J., Le Guen, Yann, Cuccaro, Michael, Farrer, Lindsay A., Napolioni, Valerio, Greicius, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2023
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628838/
https://www.ncbi.nlm.nih.gov/pubmed/37930705
http://dx.doi.org/10.1001/jamaneurol.2023.3599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628838/
https://www.ncbi.nlm.nih.gov/pubmed/37930705
http://dx.doi.org/10.1001/jamaneurol.2023.3599

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