Conformationally Selective 2-Aminotetralin Ligands Targeting the alpha2A- and alpha2C-Adrenergic Receptors

[Image: see text] Many important physiological processes are mediated by alpha2A- and alpha2C-adrenergic receptors (α2Rs), a subtype of class A G protein-coupled receptors (GPCRs). However, α2R signaling is poorly understood, and there are few approved medications targeting these receptors. Drug dis...

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Detalles Bibliográficos
Autores principales: Fragola, Nicholas R., Brems, Brittany M., Mukherjee, Munmun, Cui, Meng, Booth, Raymond G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628895/
https://www.ncbi.nlm.nih.gov/pubmed/37104867
http://dx.doi.org/10.1021/acschemneuro.3c00148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628895/
https://www.ncbi.nlm.nih.gov/pubmed/37104867
http://dx.doi.org/10.1021/acschemneuro.3c00148

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