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Conformationally Selective 2-Aminotetralin Ligands Targeting the alpha2A- and alpha2C-Adrenergic Receptors
[Image: see text] Many important physiological processes are mediated by alpha2A- and alpha2C-adrenergic receptors (α2Rs), a subtype of class A G protein-coupled receptors (GPCRs). However, α2R signaling is poorly understood, and there are few approved medications targeting these receptors. Drug dis...
Autores principales: | Fragola, Nicholas R., Brems, Brittany M., Mukherjee, Munmun, Cui, Meng, Booth, Raymond G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628895/ https://www.ncbi.nlm.nih.gov/pubmed/37104867 http://dx.doi.org/10.1021/acschemneuro.3c00148 |
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