Cargando…

Recent synthetic strategies of spiro-azetidin-2-one, -pyrrolidine, -indol(one) and -pyran derivatives-a review

Spiro-heterocycles have received special attention in medicinal chemistry because of their promising biological activity. Over the years, many synthetic methodologies have been established for the construction of spirocyclic compounds. Spiro heterocycles such as spiro-azetidin-2-one, -pyrrolidine, -...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alshammari, Mohammed B., Aly, Ashraf A., Ahmad, Akil, Brown, Alan B., Mohamed, Asmaa H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628897/ https://www.ncbi.nlm.nih.gov/pubmed/37942448 http://dx.doi.org/10.1039/d3ra06054c

Ejemplares similares

Aqua/Mechanochemical Mediated Synthesis of Novel Spiro [Indole–Pyrrolidine] Derivatives
por: Salami, Sodeeq Aderotimi, et al.
Publicado: (2023)

4-(9-Anthryl)-1-(2-methoxyphenyl)spiro[azetidin-3,9′-xanthen]-2-one
por: Yalçın, Şerife Pınar, et al.
Publicado: (2009)

4-(9-Anthryl)-1-(4-methoxyphenyl)spiro[azetidin-3,9′-xanthen]-2-one
por: Akkurt, Mehmet, et al.
Publicado: (2008)

4-(9-Anthryl)-1-(3-bromophenyl)spiro[azetidine-3,9′-xanthen]-2-one
por: Çelik, Ísmail, et al.
Publicado: (2009)

1-(Morpholin-4-yl)-4-(2-nitrophenyl)spiro[azetidine-3,9′-xanthen]-2-one
por: Atioğlu, Zeliha, et al.
Publicado: (2014)

Synthesis and Pharmacological Evaluation of Azetidin-2-ones and Thiazolidin-4-ones Encompassing Benzothiazole
por: Gurupadayya, B. M., et al.
Publicado: (2008)

4-(9-Anthryl)-1-(2,4-dimethoxyphenyl)spiro[azetidine-3,9′-xanthen]-2-one
por: Baktır, Zeliha, et al.
Publicado: (2009)

4-(9-Anthryl)-1-(1-naphthyl)spiro[azetidine-3,9′-xanthen]-2-one n-hexane hemisolvate
por: Akkurt, Mehmet, et al.
Publicado: (2008)

1-[3-(Morpholin-4-yl)propyl]-4-(3-nitrophenyl)spiro[azetidine-3,9′-xanthen]-2-one
por: Çelik, Ísmail, et al.
Publicado: (2014)

Synthesis and Antimicrobial Activities of Some New Azetidin-2-ones and Thiazolidin-4-ones
por: Desai, Shobha R., et al.
Publicado: (2011)

Targeted Synthesis of Complex Spiro[3H‐indole‐3,2′‐pyrrolidin]‐2(1H)‐ones by Intramolecular Cyclization of Azomethine Ylides: Highly Potent MDM2–p53 Inhibitors
por: Gollner, Andreas, et al.
Publicado: (2018)

3′-Benzoyl-1′-methyl-4′-phenylspiro[acenaphthylene-1(2H),2′-pyrrolidin]-2-one
por: Augustine, T., et al.
Publicado: (2010)

Azetidin-2-ones: structures of antimitotic compounds based on the 1-(3,4,5-trimethoxyphenyl)azetidin-2-one core
por: Twamley, Brendan, et al.
Publicado: (2020)

5-Hydroxy-2-methyl-4H-pyran-4-one
por: Shaheen, Muhammad Ashraf, et al.
Publicado: (2009)

Facile, Regio- and Diastereoselective Synthesis of Spiro-Pyrrolidine and Pyrrolizine Derivatives and Evaluation of Their Antiproliferative Activities
por: Almansour, Abdulrahman I., et al.
Publicado: (2014)

Organocatalysed one-pot three component synthesis of 3,3′-disubstituted oxindoles featuring an all-carbon quaternary center and spiro[2H-pyran-3,4′-indoline]
por: Nichinde, Chandrakant B., et al.
Publicado: (2023)

5,6-Dimethoxy-4′,5′-diphenylindane-2-spiro-3′-pyrrolidine-2′-spiro-3′′-indoline-1,2′′-dione
por: Ali, Mohamed Ashraf, et al.
Publicado: (2010)

Sonochemistry in an organocatalytic domino reaction: an expedient multicomponent access to structurally functionalized dihydropyrano[3,2-b]pyrans, spiro-pyrano[3,2-b]pyrans, and spiro-indenoquinoxaline-pyranopyrans under ambient conditions
por: Borah, Biplob, et al.
Publicado: (2022)

4′-Ferrocenyl-1′-methylacenapthylene-1-spiro-2′-pyrrolidine-3′-spiro-2′′-indane-2,1′′,3′′(1H)-trione
por: Gunasekaran, B., et al.
Publicado: (2009)

3′-(4-Chlorobenzoyl)-4′-(4-chlorophenyl)-1′-methylspiro[indoline-3,2′-pyrrolidin]-2-one
por: Srinivasan, T., et al.
Publicado: (2011)

3′-Hydroxymethyl-1′-methyl-3′-nitro-4′-(o-tolyl)spiro[indoline-3,2′-pyrrolidin]-2-one
por: Gangadharan, Rajeswari, et al.
Publicado: (2010)

5-(Diphenylmethylidene)pyrrolidin-2-one
por: Hsu, Tzu-Fang, et al.
Publicado: (2012)

Synthesis of Some Aldoxime Derivatives of 4H-Pyran-4-ones†
por: Abrishami, Fateme, et al.
Publicado: (2002)

1′′-Benzyl-1′-methyl-4′-(naphthalen-1-yl)naphthalene-2-spiro-3′-pyrrolidine-2′-spiro-3′′-indoline-1,2′′-dione
por: Selvanayagam, S., et al.
Publicado: (2011)

4-(9-Anthryl)-1-phenylspiro[azetidine-3,9′-xanthen]-2-one
por: Çelik, Ísmail, et al.
Publicado: (2009)

1-Benzyl-4′,5′-diphenylpiperidine-3-spiro-3′-pyrrolidine-2′-spiro-3′′-indoline-4,2′′-dione
por: Suresh, J., et al.
Publicado: (2008)

1′-Methyl-2,2′′-dioxoindoline-3-spiro-2′-pyrrolidine-3′-spiro-3′′-indoline-4′,4′-dicarbonitrile
por: Ramesh, P., et al.
Publicado: (2009)

An Expedient Regio- and Diastereoselective Synthesis of Hybrid Frameworks with Embedded Spiro[9,10]dihydroanthracene [9,3′]-pyrrolidine and Spiro[oxindole-3,2′-pyrrolidine] Motifs via an Ionic Liquid-Mediated Multicomponent Reaction
por: Arumugam, Natarajan, et al.
Publicado: (2015)

5,6-Dimethyl-4-phenyl-2H-pyran-2-one
por: Xu, Hai-Yun, et al.
Publicado: (2012)

One-Pot Route from Halogenated Amides to Piperidines and Pyrrolidines
por: Song, Qiao, et al.
Publicado: (2022)

Design, Synthesis, and Biological Evaluation of Novel Fused Spiro-4H-Pyran Derivatives as Bacterial Biofilm Disruptor
por: Saigal,, et al.
Publicado: (2019)

Synthesis and evaluation of antimicrobial activity, cytotoxic and pro-apoptotic effects of novel spiro-4H-pyran derivatives
por: Safari, Fatemeh, et al.
Publicado: (2019)

Cyclohexane-1-spiro-2′-imidazolidine-5′-spiro-1′′-cyclohexan-4′-one
por: Kavitha, T., et al.
Publicado: (2010)

A Facile One-Pot Construction of Succinimide-Fused Spiro[Pyrrolidine-2,3′-Oxindoles] via 1,3-Dipolar Cycloaddition Involving 3-Amino Oxindoles and Maleimides
por: Jin, Lunqiang, et al.
Publicado: (2018)

Synthesis of Dihydrouracils Spiro-Fused to Pyrrolidines: Druglike Molecules Based on the 2-Arylethyl Amine Scaffold
por: Blanco-Ania, Daniel, et al.
Publicado: (2010)

5′′-(4-Chlorobenzylidene)-1′,1′′-dimethyl-3′-phenylacenaphthene-1-spiro-2′-pyrrolidine-3′-spiro-3′′-pyridine-2,4′′-dione
por: Pandiarajan, S., et al.
Publicado: (2007)

Recent Advances in the Synthesis of 2H-Pyrans
por: Tejedor, David, et al.
Publicado: (2019)

Synthesis of thiazolidin-4-ones and thiazinan-4-ones from 1-(2-aminoethyl)pyrrolidine as acetylcholinesterase inhibitors
por: das Neves, Adriana M., et al.
Publicado: (2019)

Spiro[cyclopropane-1,3′-indolin]-2′-one
por: Yuan, Maosen, et al.
Publicado: (2011)

Design and synthesis of new thiazolidinone/uracil derivatives as antiproliferative agents targeting EGFR and/or BRAF(V600E)
por: Alshammari, Mohammed B., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_t7907293h6lfbiifb29tj7c0bb