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Spatiotemporal roles of AMPK in PARP-1- and autophagy-dependent retinal pigment epithelial cell death caused by UVA

BACKGROUND: Although stimulating autophagy caused by UV has been widely demonstrated in skin cells to exert cell protection, it remains unknown the cellular events in UVA-treated retinal pigment epithelial (RPE) cells. METHODS: Human ARPE-19 cells were used to measure cell viability, mitochondrial r...

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Detalles Bibliográficos
Autores principales: Wu, Anthony Yan-Tang, Sekar, Ponarulselvam, Huang, Duen-Yi, Hsu, Shu-Hao, Chan, Chi-Ming, Lin, Wan-Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629085/
https://www.ncbi.nlm.nih.gov/pubmed/37936170
http://dx.doi.org/10.1186/s12929-023-00978-4