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Upregulating miR-181b promotes ferroptosis in osteoarthritic chondrocytes by inhibiting SLC7A11

BACKGROUND: Osteoarthritis (OA) is a common disease with a complex pathology. This study aimed to investigate the correlation between the aberrant upregulation of miR-181b and ferroptosis in chondrocytes during the progression of OA. METHODS: An OA cell model was constructed with erastin. Ferrostati...

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Detalles Bibliográficos
Autores principales: Wang, Dexin, Fang, Yu, Lin, Liang, Long, Wensuo, Wang, Lei, Yu, Liwei, Deng, Huaiming, Wang, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629093/
https://www.ncbi.nlm.nih.gov/pubmed/37932746
http://dx.doi.org/10.1186/s12891-023-07003-7

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