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Inhibition of SARS-CoV-2 infection in human airway epithelium with a xeno-nucleic acid aptamer
BACKGROUND: SARS-CoV-2, the agent responsible for the COVID-19 pandemic, enters cells through viral spike glycoprotein binding to the cellular receptor, angiotensin-converting enzyme 2 (ACE2). Given the lack of effective antivirals targeting SARS-CoV-2, we previously utilized systematic evolution of...
Autores principales: | Razi, Niayesh, Li, Weizhong, Ignacio, Maxinne A., Loube, Jeffrey M., Agostino, Eva L., Zhu, Xiaoping, Scull, Margaret A., DeStefano, Jeffrey J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629106/ https://www.ncbi.nlm.nih.gov/pubmed/37932762 http://dx.doi.org/10.1186/s12931-023-02590-4 |
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