Inhibition of SARS-CoV-2 infection in human airway epithelium with a xeno-nucleic acid aptamer

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BACKGROUND: SARS-CoV-2, the agent responsible for the COVID-19 pandemic, enters cells through viral spike glycoprotein binding to the cellular receptor, angiotensin-converting enzyme 2 (ACE2). Given the lack of effective antivirals targeting SARS-CoV-2, we previously utilized systematic evolution of...

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Detalles Bibliográficos
Autores principales: Razi, Niayesh, Li, Weizhong, Ignacio, Maxinne A., Loube, Jeffrey M., Agostino, Eva L., Zhu, Xiaoping, Scull, Margaret A., DeStefano, Jeffrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629106/
https://www.ncbi.nlm.nih.gov/pubmed/37932762
http://dx.doi.org/10.1186/s12931-023-02590-4
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