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Tau reduction attenuates autism-like features in Fmr1 knockout mice

BACKGROUND: Fragile X syndrome (FXS) is a leading cause of autism spectrum disorder (ASD) and resulted from a loss of the FMR1-encoded fragile X messenger ribonucleoprotein 1 (FMRP) protein due to large CGG repeat expansions in the promoter region of the FMR1 gene. The microtubule-associated protein...

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Detalles Bibliográficos
Autores principales:	Zhao, Shanshan, Jiang, Xiangyu, Han, Linkun, Jiang, Yiru, Wang, Yong, Meng, Jian, Zhu, Xiang, Zhang, Xian, Luo, Hong, Zhang, Yun-wu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629153/ https://www.ncbi.nlm.nih.gov/pubmed/37936174 http://dx.doi.org/10.1186/s13229-023-00574-1

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