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SETD2 deficiency promotes renal fibrosis through the TGF‐β/Smad signalling pathway in the absence of VHL

BACKGROUND: Renal fibrosis is the final development pathway and the most common pathological manifestation of chronic kidney disease. Epigenetic alteration is a significant intrinsic factor contributing to the development of renal fibrosis. SET domain‐containing 2 (SETD2) is the sole histone H3K36 t...

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Detalles Bibliográficos
Autores principales: Liu, Changwei, Ni, Li, Li, Xiaoxue, Rao, Hanyu, Feng, Wenxin, Zhu, Yiwen, Zhang, Wei, Ma, Chunxiao, Xu, Yue, Gui, Liming, Wang, Ziyi, Aji, Rebiguli, Xu, Jin, Gao, Wei‐Qiang, Li, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629155/
https://www.ncbi.nlm.nih.gov/pubmed/37933774
http://dx.doi.org/10.1002/ctm2.1468

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