Differential Proteome Profiling Analysis under Pesticide Stress by the Use of a Nano-UHPLC-MS/MS Untargeted Proteomic-Based Approach on a 3D-Developed Neurospheroid Model: Identification of Protein Interactions, Prognostic Biomarkers, and Potential Therapeutic Targets in Human IDH Mutant High-Grade Gliomas

[Image: see text] High-grade gliomas represent the most common group of infiltrative primary brain tumors in adults associated with high invasiveness, agressivity, and resistance to therapy, which highlights the need to develop potent drugs with novel mechanisms of action. The aim of this study is t...

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Detalles Bibliográficos
Autores principales: Louati, Kaouthar, Maalej, Amina, Kolsi, Fatma, Kallel, Rim, Gdoura, Yassine, Borni, Mahdi, Hakim, Leila Sellami, Zribi, Rania, Choura, Sirine, Sayadi, Sami, Chamkha, Mohamed, Mnif, Basma, Khemakhem, Zouheir, Boudawara, Tahya Sellami, Boudawara, Mohamed Zaher, Safta, Fathi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629271/
https://www.ncbi.nlm.nih.gov/pubmed/37651309
http://dx.doi.org/10.1021/acs.jproteome.3c00395

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