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Topiramate alters the gut microbiome to aid in its anti-seizure effect

INTRODUCTION: There is a growing interest in the role of the gut microbiota in epilepsy, however, it is unclear if anti-seizure medications (ASMs) play a role in the gut-brain axis. To test this, we investigated the impact of the ASM topiramate on the gut microbiome of mice. METHODS: C57BL/6J mice w...

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Detalles Bibliográficos
Autores principales:	Thai, K'Ehleyr, Taylor, Michael W., Fernandes, Tatiane, Akinade, Eunice A., Campbell, Susan L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629356/ https://www.ncbi.nlm.nih.gov/pubmed/37942078 http://dx.doi.org/10.3389/fmicb.2023.1242856

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