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Dual effector population modification gene-drive strains of the African malaria mosquitoes, Anopheles gambiae and Anopheles coluzzii

Proposed genetic approaches for reducing human malaria include population modification, which introduces genes into vector mosquitoes to reduce or prevent parasite transmission. We demonstrate the potential of Cas9/guide RNA (gRNA)–based gene-drive systems linked to dual antiparasite effector genes...

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Detalles Bibliográficos
Autores principales:	Carballar-Lejarazú, Rebeca, Dong, Yuemei, Pham, Thai Binh, Tushar, Taylor, Corder, Rodrigo M., Mondal, Agastya, Sánchez C., Héctor M., Lee, Hsu-Feng, Marshall, John M., Dimopoulos, George, James, Anthony A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2023
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629562/ https://www.ncbi.nlm.nih.gov/pubmed/37428915 http://dx.doi.org/10.1073/pnas.2221118120

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