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The effect of mindfulness on decision-making, inhibitory control, and impulsivity of substance use disorder in-treatment patients: A randomized clinical trial

This study aimed to investigate the effects of Mindfulness-Based Relapse Prevention (MBRP) in decision-making, inhibitory control and impulsivity compared to Treatment as Usual (TAU) for individuals with Substance Use Disorders (SUD’s) in Brazil. A randomized clinical trial was conducted with partic...

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Autores principales: Donate, Ana Paula Gonçalves, de Macedo, Elizeu Coutinho, Bedendo, André, Félix Júnior, Itamar, Gallo, Giovanna Gonçalves, Opaleye, Emérita Sátiro, Noto, Ana Regina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629638/
https://www.ncbi.nlm.nih.gov/pubmed/37934743
http://dx.doi.org/10.1371/journal.pone.0293502
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author Donate, Ana Paula Gonçalves
de Macedo, Elizeu Coutinho
Bedendo, André
Félix Júnior, Itamar
Gallo, Giovanna Gonçalves
Opaleye, Emérita Sátiro
Noto, Ana Regina
author_facet Donate, Ana Paula Gonçalves
de Macedo, Elizeu Coutinho
Bedendo, André
Félix Júnior, Itamar
Gallo, Giovanna Gonçalves
Opaleye, Emérita Sátiro
Noto, Ana Regina
author_sort Donate, Ana Paula Gonçalves
collection PubMed
description This study aimed to investigate the effects of Mindfulness-Based Relapse Prevention (MBRP) in decision-making, inhibitory control and impulsivity compared to Treatment as Usual (TAU) for individuals with Substance Use Disorders (SUD’s) in Brazil. A randomized clinical trial was conducted with participants from a therapeutic community (n = 122). Decision-making (Iowa Gambling Task), impulsivity dimensions (UPPS-P Scale), and inhibitory control (Stroop Color-Word Test) were assessed before and after the MBRP 8-week intervention. GLM Multivariate analysis was used to evaluate the effects of MBRP on different impulsivity measures. The results showed that MBRP+TAU improved the general decision-making score (p = 0,008) compared to TAU. However, no significant effects were found in impulsivity dimensions and inhibitory control in individuals with SUDs in the therapeutic community. This study found improvement in decision-making in the total IGT score; however, no effect for self-reported impulsivity and inhibitory control among middle-aged patients after an 8-weeks intervention of MBRP protocol in an inpatient setting. It adds information to the subject, with implications and possible directions to be followed by the next clinical trials with patients with SUDs in treatment. Trial registration: EnsaiosClinicos.gov.br: RBR-6c9njc.
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spelling pubmed-106296382023-11-08 The effect of mindfulness on decision-making, inhibitory control, and impulsivity of substance use disorder in-treatment patients: A randomized clinical trial Donate, Ana Paula Gonçalves de Macedo, Elizeu Coutinho Bedendo, André Félix Júnior, Itamar Gallo, Giovanna Gonçalves Opaleye, Emérita Sátiro Noto, Ana Regina PLoS One Research Article This study aimed to investigate the effects of Mindfulness-Based Relapse Prevention (MBRP) in decision-making, inhibitory control and impulsivity compared to Treatment as Usual (TAU) for individuals with Substance Use Disorders (SUD’s) in Brazil. A randomized clinical trial was conducted with participants from a therapeutic community (n = 122). Decision-making (Iowa Gambling Task), impulsivity dimensions (UPPS-P Scale), and inhibitory control (Stroop Color-Word Test) were assessed before and after the MBRP 8-week intervention. GLM Multivariate analysis was used to evaluate the effects of MBRP on different impulsivity measures. The results showed that MBRP+TAU improved the general decision-making score (p = 0,008) compared to TAU. However, no significant effects were found in impulsivity dimensions and inhibitory control in individuals with SUDs in the therapeutic community. This study found improvement in decision-making in the total IGT score; however, no effect for self-reported impulsivity and inhibitory control among middle-aged patients after an 8-weeks intervention of MBRP protocol in an inpatient setting. It adds information to the subject, with implications and possible directions to be followed by the next clinical trials with patients with SUDs in treatment. Trial registration: EnsaiosClinicos.gov.br: RBR-6c9njc. Public Library of Science 2023-11-07 /pmc/articles/PMC10629638/ /pubmed/37934743 http://dx.doi.org/10.1371/journal.pone.0293502 Text en © 2023 Donate et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Donate, Ana Paula Gonçalves
de Macedo, Elizeu Coutinho
Bedendo, André
Félix Júnior, Itamar
Gallo, Giovanna Gonçalves
Opaleye, Emérita Sátiro
Noto, Ana Regina
The effect of mindfulness on decision-making, inhibitory control, and impulsivity of substance use disorder in-treatment patients: A randomized clinical trial
title The effect of mindfulness on decision-making, inhibitory control, and impulsivity of substance use disorder in-treatment patients: A randomized clinical trial
title_full The effect of mindfulness on decision-making, inhibitory control, and impulsivity of substance use disorder in-treatment patients: A randomized clinical trial
title_fullStr The effect of mindfulness on decision-making, inhibitory control, and impulsivity of substance use disorder in-treatment patients: A randomized clinical trial
title_full_unstemmed The effect of mindfulness on decision-making, inhibitory control, and impulsivity of substance use disorder in-treatment patients: A randomized clinical trial
title_short The effect of mindfulness on decision-making, inhibitory control, and impulsivity of substance use disorder in-treatment patients: A randomized clinical trial
title_sort effect of mindfulness on decision-making, inhibitory control, and impulsivity of substance use disorder in-treatment patients: a randomized clinical trial
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629638/
https://www.ncbi.nlm.nih.gov/pubmed/37934743
http://dx.doi.org/10.1371/journal.pone.0293502
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