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Unannotated microprotein EMBOW regulates the interactome and chromatin and mitotic functions of WDR5

The conserved WD40-repeat protein WDR5 interacts with multiple proteins both inside and outside the nucleus. However, it is currently unclear whether and how the distribution of WDR5 between complexes is regulated. Here, we show that an unannotated microprotein EMBOW (endogenous microprotein binder...

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Detalles Bibliográficos
Autores principales: Chen, Yanran, Su, Haomiao, Zhao, Jianing, Na, Zhenkun, Jiang, Kevin, Bacchiocchi, Antonella, Loh, Ken H., Halaban, Ruth, Wang, Zhentian, Cao, Xiongwen, Slavoff, Sarah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629662/
https://www.ncbi.nlm.nih.gov/pubmed/37725512
http://dx.doi.org/10.1016/j.celrep.2023.113145

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