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Merging short and stranded long reads improves transcript assembly

Long-read RNA sequencing has arisen as a counterpart to short-read sequencing, with the potential to capture full-length isoforms, albeit at the cost of lower depth. Yet this potential is not fully realized due to inherent limitations of current long-read assembly methods and underdeveloped approach...

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Detalles Bibliográficos
Autores principales: Kainth, Amoldeep S., Haddad, Gabriela A., Hall, Johnathon M., Ruthenburg, Alexander J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629667/
https://www.ncbi.nlm.nih.gov/pubmed/37883581
http://dx.doi.org/10.1371/journal.pcbi.1011576