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Merging short and stranded long reads improves transcript assembly
Long-read RNA sequencing has arisen as a counterpart to short-read sequencing, with the potential to capture full-length isoforms, albeit at the cost of lower depth. Yet this potential is not fully realized due to inherent limitations of current long-read assembly methods and underdeveloped approach...
Autores principales: | Kainth, Amoldeep S., Haddad, Gabriela A., Hall, Johnathon M., Ruthenburg, Alexander J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629667/ https://www.ncbi.nlm.nih.gov/pubmed/37883581 http://dx.doi.org/10.1371/journal.pcbi.1011576 |
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