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Pluripotent stem cell-derived neural progenitor cells can be used to model effects of IL-6 on human neurodevelopment

Maternal immune activation (MIA) increases the risks for neurodevelopmental disorders in offspring through inflammatory cytokines, including interleukin-6 (IL-6). We therefore aimed to establish a human two-dimensional (2D) in vitro neural model to investigate the effects of IL-6 exposure on neurode...

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Detalles Bibliográficos
Autores principales: Sarieva, Kseniia, Hildebrand, Felix, Kagermeier, Theresa, Yentür, Zeynep, Becker, Katharina, Mayer, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629675/
https://www.ncbi.nlm.nih.gov/pubmed/37921007
http://dx.doi.org/10.1242/dmm.050306