Cargando…
Pluripotent stem cell-derived neural progenitor cells can be used to model effects of IL-6 on human neurodevelopment
Maternal immune activation (MIA) increases the risks for neurodevelopmental disorders in offspring through inflammatory cytokines, including interleukin-6 (IL-6). We therefore aimed to establish a human two-dimensional (2D) in vitro neural model to investigate the effects of IL-6 exposure on neurode...
Autores principales: | Sarieva, Kseniia, Hildebrand, Felix, Kagermeier, Theresa, Yentür, Zeynep, Becker, Katharina, Mayer, Simone |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629675/ https://www.ncbi.nlm.nih.gov/pubmed/37921007 http://dx.doi.org/10.1242/dmm.050306 |
Ejemplares similares
-
Human brain organoid model of maternal immune activation identifies radial glia cells as selectively vulnerable
por: Sarieva, Kseniia, et al.
Publicado: (2023) -
Inducible Forward Programming of Human Pluripotent Stem Cells to Hemato-endothelial Progenitor Cells with Hematopoietic Progenitor Potential
por: Lange, Lucas, et al.
Publicado: (2019) -
Generation of pancreatic progenitors from human pluripotent stem cells by small molecules
por: Jiang, Yuqian, et al.
Publicado: (2021) -
Integrated Genomic Analysis of Diverse Induced Pluripotent Stem Cells from the Progenitor Cell Biology Consortium
por: Salomonis, Nathan, et al.
Publicado: (2016) -
The Effects of Environmental Adversities on Human Neocortical Neurogenesis Modeled in Brain Organoids
por: Sarieva, Kseniia, et al.
Publicado: (2021)