Stability and Inactivation of Monkeypox Virus on Inanimate Surfaces

The spread of nonzoonotic monkeypox virus (MPXV) infections necessitates the reevaluation of hygiene measures. To date, only limited data are available on MPXV surface stability. Here, we evaluate the stability of infectious MPXV on stainless steel stored at different temperatures, while using diffe...

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Autores principales: Meister, Toni Luise, Brüggemann, Yannick, Todt, Daniel, Tao, Ronny, Müller, Lisa, Steinmann, Jochen, Steinmann, Joerg, Timm, Joerg, Drexler, Ingo, Steinmann, Eike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629702/
https://www.ncbi.nlm.nih.gov/pubmed/37129073
http://dx.doi.org/10.1093/infdis/jiad127
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author Meister, Toni Luise
Brüggemann, Yannick
Todt, Daniel
Tao, Ronny
Müller, Lisa
Steinmann, Jochen
Steinmann, Joerg
Timm, Joerg
Drexler, Ingo
Steinmann, Eike
author_facet Meister, Toni Luise
Brüggemann, Yannick
Todt, Daniel
Tao, Ronny
Müller, Lisa
Steinmann, Jochen
Steinmann, Joerg
Timm, Joerg
Drexler, Ingo
Steinmann, Eike
author_sort Meister, Toni Luise
collection PubMed
description The spread of nonzoonotic monkeypox virus (MPXV) infections necessitates the reevaluation of hygiene measures. To date, only limited data are available on MPXV surface stability. Here, we evaluate the stability of infectious MPXV on stainless steel stored at different temperatures, while using different interfering substances to mimic environmental contamination. MPXV persistence increased with decreasing temperature. Additionally, we were able to show that MPXV could efficiently be inactivated by alcohol- and aldehyde-based surface disinfectants. These findings underline the stability of MPXV on inanimate surfaces and support the recommendations to use alcohol-based disinfectants as prevention measures or in outbreak situations.
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spelling pubmed-106297022023-11-08 Stability and Inactivation of Monkeypox Virus on Inanimate Surfaces Meister, Toni Luise Brüggemann, Yannick Todt, Daniel Tao, Ronny Müller, Lisa Steinmann, Jochen Steinmann, Joerg Timm, Joerg Drexler, Ingo Steinmann, Eike J Infect Dis Brief Report The spread of nonzoonotic monkeypox virus (MPXV) infections necessitates the reevaluation of hygiene measures. To date, only limited data are available on MPXV surface stability. Here, we evaluate the stability of infectious MPXV on stainless steel stored at different temperatures, while using different interfering substances to mimic environmental contamination. MPXV persistence increased with decreasing temperature. Additionally, we were able to show that MPXV could efficiently be inactivated by alcohol- and aldehyde-based surface disinfectants. These findings underline the stability of MPXV on inanimate surfaces and support the recommendations to use alcohol-based disinfectants as prevention measures or in outbreak situations. Oxford University Press 2023-05-02 /pmc/articles/PMC10629702/ /pubmed/37129073 http://dx.doi.org/10.1093/infdis/jiad127 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Meister, Toni Luise
Brüggemann, Yannick
Todt, Daniel
Tao, Ronny
Müller, Lisa
Steinmann, Jochen
Steinmann, Joerg
Timm, Joerg
Drexler, Ingo
Steinmann, Eike
Stability and Inactivation of Monkeypox Virus on Inanimate Surfaces
title Stability and Inactivation of Monkeypox Virus on Inanimate Surfaces
title_full Stability and Inactivation of Monkeypox Virus on Inanimate Surfaces
title_fullStr Stability and Inactivation of Monkeypox Virus on Inanimate Surfaces
title_full_unstemmed Stability and Inactivation of Monkeypox Virus on Inanimate Surfaces
title_short Stability and Inactivation of Monkeypox Virus on Inanimate Surfaces
title_sort stability and inactivation of monkeypox virus on inanimate surfaces
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629702/
https://www.ncbi.nlm.nih.gov/pubmed/37129073
http://dx.doi.org/10.1093/infdis/jiad127
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