Microglia complement signaling promotes neuronal elimination and normal brain functional connectivity

Complement signaling is thought to serve as an opsonization signal to promote the phagocytosis of synapses by microglia. However, while its role in synaptic remodeling has been demonstrated in the retino-thalamic system, it remains unclear whether complement signaling mediates synaptic pruning in th...

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Detalles Bibliográficos
Autores principales: Deivasigamani, Senthilkumar, Miteva, Mariya T, Natale, Silvia, Gutierrez-Barragan, Daniel, Basilico, Bernadette, Di Angelantonio, Silvia, Weinhard, Laetitia, Molotkov, Dmitry, Deb, Sukrita, Pape, Constantin, Bolasco, Giulia, Galbusera, Alberto, Asari, Hiroki, Gozzi, Alessandro, Ragozzino, Davide, Gross, Cornelius T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629900/
https://www.ncbi.nlm.nih.gov/pubmed/37718159
http://dx.doi.org/10.1093/cercor/bhad313

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