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Autophagy–urea cycle pathway is essential for the statin-mediated nitric oxide bioavailability in endothelial cells

Statins induce nitric oxide (NO) bioavailability by activating endothelial nitric oxide synthase via kinase- and calcium-dependent pathways in endothelial cells (ECs). However, their effect on the metabolism of L-arginine, the precursor for NO biosynthesis, and regulatory mechanism have not yet been...

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Detalles Bibliográficos
Autores principales:	Chen, Wen-Hua, Guo, Bei-Chia, Chen, Chia-Hui, Hsu, Man-Chen, Wang, Chih-Hsien, Lee, Tzong-Shyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taiwan Food and Drug Administration 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629920/ http://dx.doi.org/10.38212/2224-6614.3472

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