Evaluation of Serum Creatinine Levels with Reference Change Value in Patients Receiving Colistin Treatment

OBJECTIVE: In this study, we aimed to evaluate the serum creatinine (SCr) levels with the reference change value (RCV) in patients receiving colistin treatment. METHODS: We retrospectively recorded the SCr levels of 47 patients receiving colistin treatment before treatment and on days 3 and 7 after...

Descripción completa

Detalles Bibliográficos
Autores principales: Cinpolat, Havva Yasemin, Alkan, Sevil, Altinisik, Hatice Betul, Cakir, Dilek Ulker, Oguzman, Hamdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629923/
https://www.ncbi.nlm.nih.gov/pubmed/36883236
http://dx.doi.org/10.1093/labmed/lmad009
Descripción
Sumario:OBJECTIVE: In this study, we aimed to evaluate the serum creatinine (SCr) levels with the reference change value (RCV) in patients receiving colistin treatment. METHODS: We retrospectively recorded the SCr levels of 47 patients receiving colistin treatment before treatment and on days 3 and 7 after treatment. RCV was calculated with the asymmetrical RCV formula (Z = 1.64, P < .05). Percent (%) increase in the SCr results of the patients was compared with RCV and values exceeding RCV were regarded as statistically significant. RESULTS: The RCV was calculated as 15.6% for SCr. Compared with pretreatment values, SCr value on day 3 was 32/47 and on day 7 it was 36/47; as these results exceeded RCV, they were considered statistically significant. CONCLUSION: Use of RCV in the interpretation of results between serial measurements will provide a more rapid and sensitive method when making decisions.

Ejemplares similares