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Receptor activator of nuclear factor-kappa B is enriched in CD9-positive extracellular vesicles released by osteoclasts

AIM: Receptor activator of nuclear factor-kappa B (RANK)-containing extracellular vesicles (EVs) bind RANK-Ligand (RANKL) on osteoblasts, and thereby simultaneously inhibit bone resorption and promote bone formation. Because of this, they are attractive candidates for therapeutic bone anabolic agent...

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Detalles Bibliográficos
Autores principales: Ruan, Shaobo, Rody, Wellington J., Patel, Shivani S., Hammadi, Lina I., Martin, Macey L., de Faria, Lorraine P., Daaboul, George, Anderson, Leif S., He, Mei, Holliday, L. Shannon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629932/
https://www.ncbi.nlm.nih.gov/pubmed/37936884
http://dx.doi.org/10.20517/evcna.2023.38