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Sphingosine kinase 1 is involved in triglyceride breakdown by maintaining lysosomal integrity in brown adipocytes

Sphingosine 1-phosphate (S1P) has been implicated in brown adipose tissue (BAT) formation and energy consumption; however, the mechanistic role of sphingolipids, including S1P, in BAT remains unclear. Here, we showed that, in mice, BAT activation by cold exposure upregulated mRNA and protein express...

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Detalles Bibliográficos
Autores principales:	Morishige, Jun-ichi, Yoshioka, Kazuaki, Nakata, Hiroki, Ishimaru, Kazuhiro, Nagata, Naoto, Tanaka, Tamotsu, Takuwa, Yoh, Ando, Hitoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630120/ https://www.ncbi.nlm.nih.gov/pubmed/37751791 http://dx.doi.org/10.1016/j.jlr.2023.100450

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