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Natalizumab Treatment of Relapsing Remitting Multiple Sclerosis Has No Long-Term Effects on the Proportion of Circulating Regulatory T Cells
INTRODUCTION: Natalizumab (NTZ), a monoclonal antibody against the integrin α4β1 (VLA-4) found on activated T cells and B cells, blocks the interaction of this integrin with adhesion molecules of central nervous system (CNS) endothelial cells and lymphocyte migration through the blood–brain barrier,...
Autores principales: | Tanasescu, Radu, Frakich, Nanci, Chou, I.-Jun, Filippini, Perla, Podda, Giulio, Xin, Gao, Muraleedharan, Ranjithmenon, Jerca, Oltita, Onion, David, Constantinescu, Cris S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Healthcare
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630259/ https://www.ncbi.nlm.nih.gov/pubmed/37715885 http://dx.doi.org/10.1007/s40120-023-00539-9 |
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