Unappreciated subcontinental admixture in Europeans and European Americans and implications for genetic epidemiology studies

European-ancestry populations are recognized as stratified but not as admixed, implying that residual confounding by locus-specific ancestry can affect studies of association, polygenic adaptation, and polygenic risk scores. We integrate individual-level genome-wide data from ~19,000 European-ancest...

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Detalles Bibliográficos
Autores principales: Gouveia, Mateus H., Bentley, Amy R., Leal, Thiago P., Tarazona-Santos, Eduardo, Bustamante, Carlos D., Adeyemo, Adebowale A., Rotimi, Charles N., Shriner, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630423/
https://www.ncbi.nlm.nih.gov/pubmed/37935687
http://dx.doi.org/10.1038/s41467-023-42491-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630423/
https://www.ncbi.nlm.nih.gov/pubmed/37935687
http://dx.doi.org/10.1038/s41467-023-42491-0

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