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Unappreciated subcontinental admixture in Europeans and European Americans and implications for genetic epidemiology studies
European-ancestry populations are recognized as stratified but not as admixed, implying that residual confounding by locus-specific ancestry can affect studies of association, polygenic adaptation, and polygenic risk scores. We integrate individual-level genome-wide data from ~19,000 European-ancest...
Autores principales: | Gouveia, Mateus H., Bentley, Amy R., Leal, Thiago P., Tarazona-Santos, Eduardo, Bustamante, Carlos D., Adeyemo, Adebowale A., Rotimi, Charles N., Shriner, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630423/ https://www.ncbi.nlm.nih.gov/pubmed/37935687 http://dx.doi.org/10.1038/s41467-023-42491-0 |
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